SYT7 (synaptotagmin 7)

symbol:
SYT7
locus group:
protein-coding gene
location:
11q12.2
gene_family:
Synaptotagmins
alias symbol:
IPCA-7|SYT-VII|MGC150517
alias name:
None
entrez id:
9066
ensembl gene id:
ENSG00000011347
ucsc gene id:
uc001nrv.4
refseq accession:
NM_004200
hgnc_id:
HGNC:11514
approved reserved:
1999-07-14
11q12.2
基因染色体位置图

This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

该基因是突触基因家族的成员,编码类似,其他家庭成员的调解突触传递膜贩运的钙依赖性调节的蛋白质。在啮齿类动物类似的蛋白介导的激素分泌和溶酶体胞吐作用。在人类中,该基因的表达与前列腺癌有关。编码多种亚型选择性剪接的转录物变体已经观察到这种基因。 [由RefSeq的,2011年10月提供]

CCND1基因的碱基序列:[NCBI]
Loading Gene Browser...
SYT7基因的碱基突变:           仅显示部分snp
rs73603       rs82969       rs198763       rs10692111       rs11230745       rs11330021       rs11826678       rs66541252       rs74685492       rs75560731       rs77359675       rs112256968       rs112972256       rs113188327       rs114018293       rs114121219       rs115250175      

SYT7基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向Tm值
反向引物序列
反向Tm值
评分
CGCTACAAGAATTCCTTGGAG
59
CTGCAGGCAACTTGATAGC
59
AACTTGTCCAAGTTGCCTG
59
GGAGTTGACGAGGTCTGAG
60
AGAATTCCTTGGAGACGGT
58
CTCTGTCTAGATCATTGATAGCC
58
AGAATTCCTTGGAGACGGT
58
CTCTGTCTAGATCATTGATAGCC
58
ATGAAATCCTTCCTGGAAGG
57
GGATATTGGCAAAGTCATCCT
58
TTCAATGAGTCCTTCGCCT
59
GACAGGTAGATCTTGCCGA
59
GAGAAGAAGGCTATCAATGGC
59
CTTCTCAAGGCGTCCTCTC
60
AGAATTCCTTGGAGACGGT
58
CTCTGTCTAGATCATTGATAGCC
58
GAAATGGAGCTCCTACCCT
59
GTCCTCGAAATTGAGGGAC
58
TCCTCTTTGAAGCTGGGAG
59
AGGTGAATGGCATCTCGTC
60
      尚未收录相关数据

SYT7基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 质膜
  • 细胞质
  • 细胞外
  • 高尔基体
  • 囊泡
  • 细胞骨架
  • 内质网
  • 细胞核
  • 内体
  • 溶酶体
  • 线粒体

SYT7基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0006887
F5GX00 (UniProtKB)
IEA
GO:0016021
F5GX00 (UniProtKB)
IEA
GO:0006887
F5H8G7 (UniProtKB)
IEA
GO:0016021
F5H8G7 (UniProtKB)
IEA
GO:0001778
O43581 (UniProtKB)
ISS
GO:0005509
O43581 (UniProtKB)
IBA
GO:0005515
O43581 (UniProtKB)
IPI
GO:0005516
O43581 (UniProtKB)
ISS
GO:0005544
O43581 (UniProtKB)
ISS
GO:0005544
O43581 (UniProtKB)
IBA
GO:0005544
O43581 (UniProtKB)
NAS
GO:0005546
O43581 (UniProtKB)
ISS
GO:0005764
O43581 (UniProtKB)
ISS
GO:0005765
O43581 (UniProtKB)
IEA
GO:0005777
O43581 (UniProtKB)
ISS
GO:0005778
O43581 (UniProtKB)
IEA
GO:0005829
O43581 (UniProtKB)
IEA
GO:0005886
O43581 (UniProtKB)
IBA
GO:0006906
O43581 (UniProtKB)
IBA
GO:0006909
O43581 (UniProtKB)
ISS
GO:0008021
O43581 (UniProtKB)
ISS
GO:0016021
O43581 (UniProtKB)
IEA
GO:0017158
O43581 (UniProtKB)
IBA
GO:0019905
O43581 (UniProtKB)
IBA
GO:0030054
O43581 (UniProtKB)
IEA
GO:0030276
O43581 (UniProtKB)
IBA
GO:0030670
O43581 (UniProtKB)
IEA
GO:0030672
O43581 (UniProtKB)
IEA
GO:0031045
O43581 (UniProtKB)
IEA
GO:0032009
O43581 (UniProtKB)
ISS
GO:0036465
O43581 (UniProtKB)
ISS
GO:0042734
O43581 (UniProtKB)
IEA
GO:0043195
O43581 (UniProtKB)
IEA
GO:0045956
O43581 (UniProtKB)
IEA
GO:0046850
O43581 (UniProtKB)
ISS
GO:0048791
O43581 (UniProtKB)
ISS
GO:0048791
O43581 (UniProtKB)
IBA
GO:0050764
O43581 (UniProtKB)
ISS
GO:0050796
O43581 (UniProtKB)
ISS
GO:0070062
O43581 (UniProtKB)
IDA
GO:0070092
O43581 (UniProtKB)
ISS
GO:0090119
O43581 (UniProtKB)
ISS
GO:0090385
O43581 (UniProtKB)
ISS
GO:1990927
O43581 (UniProtKB)
ISS
GO:1990927
O43581 (UniProtKB)
ISS

可能调控 SYT7基因的相关microRNA:     

BioGrid

IntAct

mentha

String

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源

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