SSX3 (SSX family member 3)
- symbol:
- SSX3
- locus group:
- protein-coding gene
- location:
- Xp11.23
- gene_family:
- alias symbol:
- CT5.3
- alias name:
- None
- entrez id:
- 10214
- ensembl gene id:
- ENSG00000165584
- ucsc gene id:
- uc004djd.3
- refseq accession:
- NM_021014
- hgnc_id:
- HGNC:11337
- approved reserved:
- 1999-06-10
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. While some of the related SSX genes are involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas, this gene does not appear to be involved in such translocations. [provided by RefSeq, Jul 2013]
该基??因的产物属于家庭高度同源的滑膜肉瘤X（SSX）断点蛋白质。这些蛋白质可以充当转录抑制。它们也能够引发癌症患者自发的体液和细胞免疫应答，且是潜在的癌症基于疫苗免疫治疗的目标。虽然一些相关SSX基因参与T（X 18）（P11.2; q11.2），它们在所有的滑膜肉瘤特征发现易位，该基因似乎不参与这些易位。 [由RefSeq的，2013年7月提供]
基因本体信息
SSX3基因（以及对应的蛋白质）的细胞分布位置：
- 质膜
- 细胞质
- 细胞外
- 高尔基体
- 囊泡
- 细胞骨架
- 内质网
- 细胞核
- 内体
- 溶酶体
- 线粒体
SSX3基因的本体（GO）信息：
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