This gene belongs to a class of genes that are activated in tumors. These genes are expressed in tumors of different histologic types but not in normal tissues, except for spermatogenic cells and, for some, placenta. The proteins encoded by these genes appear to be strictly tumor specific, and hence may be excellent sources of antigens for cancer immunotherapy. This gene is expressed in sarcomas. [provided by RefSeq, Jul 2008]
该基因属于一类被在肿瘤中活化的基因。这些基因在不同组织学类型的肿瘤,但在正常组织中表达,除了精细胞,对于某些,胎盘。由这些基因编码的蛋白质似乎是严格肿瘤特异性,并且因此可以是抗原的癌症免疫治疗的最佳来源。该基因在肉瘤表示。 [由RefSeq的,2008年7月提供]
SAGE1基因(以及对应的蛋白质)的细胞分布位置:
SAGE1基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Breast Carcinoma | 0.001357209 | 5 | 0 | BeFree |
Malignant neoplasm of breast | 0.001085767 | 4 | 0 | BeFree |
Glioblastoma | 0.000814326 | 3 | 0 | BeFree |
Lung Neoplasms | 0.000542884 | 2 | 0 | BeFree |
melanoma | 0.000542884 | 2 | 0 | BeFree |
Malignant neoplasm of stomach | 0.000542884 | 2 | 0 | BeFree |
Tumor Progression | 0.000542884 | 2 | 0 | BeFree |
Glioma | 0.000542884 | 2 | 0 | BeFree |
Noninfiltrating Intraductal Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Squamous cell carcinoma | 0.000271442 | 1 | 0 | BeFree |
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