RCBTB2基因详情-基因数据库-基因云馆

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RCBTB2 (RCC1 and BTB domain containing protein 2)

symbol:: RCBTB2
locus group:: protein-coding gene
location:: 13q14.2
gene_family:: BTB (POZ) domain containing
alias symbol:: None
alias name:: None
entrez id:: 1102
ensembl gene id:: ENSG00000136161
ucsc gene id:: uc001vci.5
refseq accession:: NM_001268
hgnc_id:: HGNC:1914
approved reserved:: 2005-05-09

13q14.2

This gene encodes a protein containing two C-terminal BTB/POZ domains that is related to regulator of chromosome condensation (RCC). The encoded protein may act as a guanine nucleotide exchange factor. This gene is observed to be lost or underexpressed in prostate cancers. There is a pseudogene of this gene on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]

None

OMIM数据库中对CCND1基因的介绍 Wikipedia数据库中对CCND1基因的介绍

CCND1基因的碱基序列：[NCBI]

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RCBTB2基因的碱基突变：仅显示部分snp

rs10076 rs11861 rs751334 rs943278 rs943281 rs943282 rs943283 rs943284 rs977097 rs2148515 rs2274400 rs2897588 rs3085589 rs3215827 rs6561447 rs6561448 rs6561449

RCBTB2基因在不同组织中的表达： [UniProt]

正向引物序列

正向Tm值

反向引物序列

反向Tm值

评分

GTCCTTGCAACAACAGAAGG

ATGATTAGTTGTCCCATTGCC

ATATCCTGTTTACCGGGCC

TCTAGCAGTCCTACTGCCT

AAGTTGACAAAGGGACTGC

TGACAGAGTAGCCTGTACTG

AAGTAGAGGAACTGAAGATGGG

CTCACAGATCTCAAATGCCC

CATATCCTGTTTACCGGGC

CTAGCAGTCCTACTGCCTC

AGTAGAGGAACTGAAGATGGG

CCTCACAGATCTCAAATGCC

CTGATGGAGAGGTATTTGCC

GAGGGATTGGCTGATTAACTG

AAAGTTGACAAAGGGACTGC

ACAGAGTAGCCTGTACTGG

AGTAGAGGAACTGAAGATGGG

CTCACAGATCTCAAATGCCC

AAGTTGACAAAGGGACTGC

ACAGAGTAGCCTGTACTGG

尚未收录相关数据

RCBTB2基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

质膜
细胞质
细胞外
高尔基体
囊泡
细胞骨架
内质网
细胞核
内体
溶酶体
线粒体

RCBTB2基因的本体（GO）信息：

GO库代码

对应的蛋白质

来源代码

GO:0001669

B4DWG0 (UniProtKB)

IEA

GO:0005087

O95199 (UniProtKB)

TAS

GO:0005515

O95199 (UniProtKB)

IPI

GO:0005515

O95199 (UniProtKB)

IPI

GO:0043547

O95199 (UniProtKB)

IEA

可能调控 RCBTB2基因的相关microRNA：

hsa-miR-192 hsa-miR-26b

BioGrid

IntAct

mentha

String

序号	作用方式	资源库来源/分值	基因名称	基因名称

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
Prostatic Neoplasms	0.002995792	1	0	BeFree_LHGDN
Tobacco Use Disorder	0.002367032	1	0	GAD
Multiple Myeloma	0.000542884	2	0	BeFree
Prostate carcinoma	0.000271442	1	0	BeFree
Lipoma	0.000271442	1	0	BeFree
Malignant neoplasm of prostate	0.000271442	1	0	BeFree
Carcinogenesis	0.000271442	1	0	BeFree
Monoclonal Gammapathies	0.000271442	1	0	BeFree