NUP50基因详情-基因数据库-基因云馆

NUP50 (nucleoporin 50)

symbol:: NUP50
locus group:: protein-coding gene
location:: 22q13.31
gene_family:
alias symbol:: None
alias name:: None
entrez id:: 10762
ensembl gene id:: ENSG00000093000
ucsc gene id:: uc003bfr.4
refseq accession:: NM_007172
hgnc_id:: HGNC:8065
approved reserved:: 2000-02-16

22q13.31

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

的核孔复合是跨核膜延伸，形成一种调节细胞核与细胞质之间的大分子的流程的网关大规模结构。核孔蛋白是在真核细胞的核孔复合物的主要组成部分。由该基因编码的蛋白质是含有核孔蛋白，其功能如输入蛋白-α的可溶性辅助因子的FG-重复的成员：β调控核蛋白导入。该基因的假基因是在染色体5 6发现，并已发现了该基因14的两个编码不同同种型的转录变体。 [由RefSeq的，2008年7月提供]

OMIM数据库中对CCND1基因的介绍 Wikipedia数据库中对CCND1基因的介绍

CCND1基因的碱基序列：[NCBI]

Loading Gene Browser...

NUP50基因的碱基突变：仅显示部分snp

rs132842 rs132843 rs132844 rs132845 rs132846 rs132847 rs132848 rs132849 rs132850 rs132851 rs132852 rs132853 rs132854 rs132855 rs132856 rs132857 rs477067

NUP50基因在不同组织中的表达： [UniProt]

正向引物序列

正向Tm值

反向引物序列

反向Tm值

评分

AACCTACAGCAAATCAGAAGAC

58

ATGTTGCCTAAATTGGTGTCTG

59

AGTCTCTTCACCATTTCCCA

59

TCTTCATCTCCACCTTTGCA

59

AGATGAAGCTGAAGAGGTGG

60

GCGCTTTGCTTTCTTTATGG

59

TTGGGATCAAGAAGATGAAGCT

60

TCTTCGGCTTTAGTTTATAGCC

58

AGTCTCTTCACCATTTCCCA

59

TCTTCATCTCCACCTTTGCA

59

GGAAACAACATAACCAGTGC

58

CTTCATCTCCACCAAAGGC

59

AGTCTCTTCACCATTTCCCA

59

TCTTCATCTCCACCTTTGCA

59

GAGATGAAGAAACTGAGGCAC

59

TTCTAGCTGTGAGAACTTGGG

59

CGACTCGAGTGAGACTCTC

59

TAGCTGTGAGAACTTGGGC

60

TGGATTTGAAGTCATGGGAG

58

TTTCCTCAACTGGATAAGCTC

58

尚未收录相关数据

NUP50基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

质膜
细胞质
细胞外
高尔基体
囊泡
细胞骨架
内质网
细胞核
内体
溶酶体
线粒体

NUP50基因的本体（GO）信息：

GO库代码

对应的蛋白质

来源代码

GO:0005643

B0QY21 (UniProtKB)

IEA

GO:0005654

B0QY21 (UniProtKB)

IDA

GO:0005737

B0QY21 (UniProtKB)

IDA

GO:0031965

B0QY21 (UniProtKB)

IDA

GO:0046907

B0QY21 (UniProtKB)

IEA

GO:0005643

B1AHA5 (UniProtKB)

IEA

GO:0005654

B1AHA5 (UniProtKB)

IDA

GO:0005737

B1AHA5 (UniProtKB)

IDA

GO:0016021

B1AHA5 (UniProtKB)

IEA

GO:0031965

B1AHA5 (UniProtKB)

IDA

GO:0005643

F2Z3L9 (UniProtKB)

IEA

GO:0005515

Q9UKX7 (UniProtKB)

IPI

GO:0005515

Q9UKX7 (UniProtKB)

IPI

GO:0005515

Q9UKX7 (UniProtKB)

IPI

GO:0005515

Q9UKX7 (UniProtKB)

IPI

GO:0005515

Q9UKX7 (UniProtKB)

IPI

GO:0005515

Q9UKX7 (UniProtKB)

IPI

GO:0005515

Q9UKX7 (UniProtKB)

IPI

GO:0005515

Q9UKX7 (UniProtKB)

IPI

GO:0005515

Q9UKX7 (UniProtKB)

IPI

GO:0005515

Q9UKX7 (UniProtKB)

IPI

GO:0005515

Q9UKX7 (UniProtKB)

IPI

GO:0005643

Q9UKX7 (UniProtKB)

IEA

GO:0005654

Q9UKX7 (UniProtKB)

IDA

GO:0005654

Q9UKX7 (UniProtKB)

TAS

GO:0005654

Q9UKX7 (UniProtKB)

TAS

GO:0005654

Q9UKX7 (UniProtKB)

TAS

GO:0005654

Q9UKX7 (UniProtKB)

TAS

GO:0005654

Q9UKX7 (UniProtKB)

TAS

GO:0005654

Q9UKX7 (UniProtKB)

TAS

GO:0005654

Q9UKX7 (UniProtKB)

TAS

GO:0005654

Q9UKX7 (UniProtKB)

TAS

GO:0005654

Q9UKX7 (UniProtKB)

TAS

GO:0005654

Q9UKX7 (UniProtKB)

TAS

GO:0005654

Q9UKX7 (UniProtKB)

TAS

GO:0005654

Q9UKX7 (UniProtKB)

TAS

GO:0005654

Q9UKX7 (UniProtKB)

TAS

GO:0005654

Q9UKX7 (UniProtKB)

TAS

GO:0005654

Q9UKX7 (UniProtKB)

TAS

GO:0005654

Q9UKX7 (UniProtKB)

TAS

GO:0005654

Q9UKX7 (UniProtKB)

TAS

GO:0005654

Q9UKX7 (UniProtKB)

TAS

GO:0005654

Q9UKX7 (UniProtKB)

TAS

GO:0005654

Q9UKX7 (UniProtKB)

TAS

GO:0005654

Q9UKX7 (UniProtKB)

TAS

GO:0005737

Q9UKX7 (UniProtKB)

IDA

GO:0006406

Q9UKX7 (UniProtKB)

TAS

GO:0006406

Q9UKX7 (UniProtKB)

TAS

GO:0006406

Q9UKX7 (UniProtKB)

TAS

GO:0006409

Q9UKX7 (UniProtKB)

TAS

GO:0006606

Q9UKX7 (UniProtKB)

IBA

GO:0007077

Q9UKX7 (UniProtKB)

TAS

GO:0008536

Q9UKX7 (UniProtKB)

IBA

GO:0010827

Q9UKX7 (UniProtKB)

TAS

GO:0016032

Q9UKX7 (UniProtKB)

TAS

GO:0016925

Q9UKX7 (UniProtKB)

TAS

GO:0016925

Q9UKX7 (UniProtKB)

TAS

GO:0016925

Q9UKX7 (UniProtKB)

TAS

GO:0019083

Q9UKX7 (UniProtKB)

TAS

GO:0031047

Q9UKX7 (UniProtKB)

TAS

GO:0031965

Q9UKX7 (UniProtKB)

IDA

GO:0031965

Q9UKX7 (UniProtKB)

IDA

GO:0075733

Q9UKX7 (UniProtKB)

TAS

GO:1900034

Q9UKX7 (UniProtKB)

TAS

GO:0005643

X6RKQ2 (UniProtKB)

IEA

GO:0005654

X6RKQ2 (UniProtKB)

IDA

GO:0005737

X6RKQ2 (UniProtKB)

IDA

GO:0031965

X6RKQ2 (UniProtKB)

IDA

可能调控 NUP50基因的相关microRNA：

hsa-miR-1 hsa-miR-103 hsa-miR-124 hsa-miR-16 hsa-miR-196a hsa-miR-340 hsa-miR-615-3p hsa-miR-877*

Reactome

MINT

BioGrid

IntAct

mentha

String

序号	作用方式	资源库来源/分值	基因名称	基因名称

KEGG
Reactomepathway

名称
3013 RNA transport [PATH:hsa03013]

名称
Antiviral mechanism by IFN-stimulated genes
Cell Cycle
Cell Cycle, Mitotic
Cellular response to heat stress
Cellular responses to stress
Cytokine Signaling in Immune system
Disease
Export of Viral Ribonucleoproteins from Nucleus
Gene Expression
Glucose transport
Hexose transport
HIV Infection
HIV Life Cycle
Host Interactions of HIV factors
Immune System
Infectious disease
Influenza Infection
Influenza Life Cycle
Influenza Viral RNA Transcription and Replication
Interactions of Rev with host cellular proteins
Interactions of Vpr with host cellular proteins
Interferon Signaling
ISG15 antiviral mechanism
Late Phase of HIV Life Cycle
M Phase
Metabolism of carbohydrates
Metabolism of non-coding RNA
Metabolism of proteins
Mitotic Prophase
NEP/NS2 Interacts with the Cellular Export Machinery
Nuclear Envelope Breakdown
Nuclear import of Rev protein
Nuclear Pore Complex (NPC) Disassembly
Post-translational protein modification
Processing of Capped Intron-Containing Pre-mRNA
Regulation of Glucokinase by Glucokinase Regulatory Protein
Regulation of HSF1-mediated heat shock response
Regulatory RNA pathways
Rev-mediated nuclear export of HIV RNA
SLC-mediated transmembrane transport
snRNP Assembly
SUMO E3 ligases SUMOylate target proteins
SUMOylation
SUMOylation of DNA damage response and repair proteins
Transcriptional regulation by small RNAs
Transmembrane transport of small molecules
Transport of Mature mRNA derived from an Intron-Containing Transcript
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNAs Derived from Intronless Transcripts
Transport of Mature Transcript to Cytoplasm
Transport of Ribonucleoproteins into the Host Nucleus
Transport of the SLBP Dependant Mature mRNA
Transport of the SLBP independent Mature mRNA
Viral Messenger RNA Synthesis
Vpr-mediated nuclear import of PICs

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
Tobacco Use Disorder	0.002367032	1	0	GAD

NUP50 (nucleoporin 50)

基因基本信息

基因基本信息

基因染色体位置

基因染色体位置

基因简述

基因简述

基因序列

基因序列

基因突变

基因突变

基因表达

基因表达

基因引物

基因引物

转录因子

转录因子

尚未收录相关数据

基因本体信息

基因相关microRNA

基因相关microRNA

基因相互作用关系

基因相互作用关系

基因通路

基因通路

基因相关疾病

基因相关疾病

基因相关服务

基因相关服务

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