NECTIN2 (nectin cell adhesion molecule 2)

基因基本信息

基因基本信息

symbol:
NECTIN2
locus group:
protein-coding gene
location:
19q13.32
gene_family:
CD molecules|V-set domain containing|C2-set domain containing|Immunoglobulin-like domain containing
alias symbol:
PVRR2|PRR2|CD112|Nectin-2
alias name:
None
entrez id:
5819
ensembl gene id:
ENSG00000130202
ucsc gene id:
uc002ozv.4
refseq accession:
NM_002856
hgnc_id:
HGNC:9707
approved reserved:
1999-11-15

基因染色体位置

基因染色体位置

19q13.32
基因染色体位置图

基因简述

基因简述

This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

该基??因编码1膜具有两个Ig样C2型结构域和Ig样V型结构域糖蛋白的单通型。这种蛋白质是粘着结的质膜组件之一。它也可以作为单纯疱疹病毒和伪狂犬病病毒的某些突变体菌株中的条目，并且它参与细胞与细胞的这些病毒传播。在这种基因的变化已在多发性硬化的严重程度的差异相关联。备用转录剪接变体，编码不同同种型，已经表征。 [由RefSeq的，2008年7月提供]

OMIM数据库中对CCND1基因的介绍     Wikipedia数据库中对CCND1基因的介绍

基因序列

基因序列

CCND1基因的碱基序列：[NCBI]
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基因突变

基因突变

NECTIN2基因的碱基突变：           仅显示部分snp

基因表达

基因表达

NECTIN2基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向Tm值
反向引物序列
反向Tm值
评分

转录因子

转录因子

      尚未收录相关数据

基因本体信息

NECTIN2基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 质膜
  • 细胞质
  • 细胞外
  • 高尔基体
  • 囊泡
  • 细胞骨架
  • 内质网
  • 细胞核
  • 内体
  • 溶酶体
  • 线粒体

NECTIN2基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0005911
K7EKE8 (UniProtKB)
IEA
GO:0007155
K7EKE8 (UniProtKB)
IEA
GO:0007286
K7EKE8 (UniProtKB)
IEA
GO:0042803
K7EKE8 (UniProtKB)
IEA
GO:0046718
K7EKE8 (UniProtKB)
IEA
GO:0046982
K7EKE8 (UniProtKB)
IEA
GO:0050839
K7EKE8 (UniProtKB)
IEA
GO:0001618
Q92692 (UniProtKB)
IEA
GO:0001675
Q92692 (UniProtKB)
IEA
GO:0002860
Q92692 (UniProtKB)
IMP
GO:0002891
Q92692 (UniProtKB)
IMP
GO:0005102
Q92692 (UniProtKB)
IBA
GO:0005515
Q92692 (UniProtKB)
IPI
GO:0005515
Q92692 (UniProtKB)
IPI
GO:0005515
Q92692 (UniProtKB)
IPI
GO:0005515
Q92692 (UniProtKB)
IPI
GO:0005515
Q92692 (UniProtKB)
IPI
GO:0005515
Q92692 (UniProtKB)
IPI
GO:0005515
Q92692 (UniProtKB)
IPI
GO:0005515
Q92692 (UniProtKB)
IPI
GO:0005515
Q92692 (UniProtKB)
IPI
GO:0005515
Q92692 (UniProtKB)
IPI
GO:0005515
Q92692 (UniProtKB)
IPI
GO:0005515
Q92692 (UniProtKB)
IPI
GO:0005886
Q92692 (UniProtKB)
TAS
GO:0005886
Q92692 (UniProtKB)
TAS
GO:0005886
Q92692 (UniProtKB)
TAS
GO:0005886
Q92692 (UniProtKB)
TAS
GO:0005886
Q92692 (UniProtKB)
TAS
GO:0005886
Q92692 (UniProtKB)
TAS
GO:0005887
Q92692 (UniProtKB)
IBA
GO:0005911
Q92692 (UniProtKB)
IDA
GO:0005913
Q92692 (UniProtKB)
IBA
GO:0005915
Q92692 (UniProtKB)
ISS
GO:0005925
Q92692 (UniProtKB)
IDA
GO:0007010
Q92692 (UniProtKB)
IEA
GO:0007156
Q92692 (UniProtKB)
IDA
GO:0007157
Q92692 (UniProtKB)
IBA
GO:0007165
Q92692 (UniProtKB)
IEA
GO:0007286
Q92692 (UniProtKB)
ISS
GO:0007289
Q92692 (UniProtKB)
IEA
GO:0008037
Q92692 (UniProtKB)
IBA
GO:0009566
Q92692 (UniProtKB)
IEA
GO:0009986
Q92692 (UniProtKB)
IDA
GO:0015026
Q92692 (UniProtKB)
TAS
GO:0016021
Q92692 (UniProtKB)
IDA
GO:0019064
Q92692 (UniProtKB)
IDA
GO:0030382
Q92692 (UniProtKB)
IEA
GO:0032990
Q92692 (UniProtKB)
IEA
GO:0033005
Q92692 (UniProtKB)
IMP
GO:0034332
Q92692 (UniProtKB)
TAS
GO:0042271
Q92692 (UniProtKB)
IMP
GO:0042802
Q92692 (UniProtKB)
IPI
GO:0042802
Q92692 (UniProtKB)
IPI
GO:0042803
Q92692 (UniProtKB)
IEA
GO:0042803
Q92692 (UniProtKB)
IPI
GO:0042803
Q92692 (UniProtKB)
IPI
GO:0044406
Q92692 (UniProtKB)
IDA
GO:0044782
Q92692 (UniProtKB)
IEA
GO:0045954
Q92692 (UniProtKB)
IMP
GO:0046596
Q92692 (UniProtKB)
IDA
GO:0046814
Q92692 (UniProtKB)
IDA
GO:0046982
Q92692 (UniProtKB)
IEA
GO:0050776
Q92692 (UniProtKB)
TAS
GO:0050839
Q92692 (UniProtKB)
IPI
GO:0050839
Q92692 (UniProtKB)
IPI
GO:0051654
Q92692 (UniProtKB)
IEA
GO:0060370
Q92692 (UniProtKB)
IDA
GO:0070062
Q92692 (UniProtKB)
IDA
GO:0070062
Q92692 (UniProtKB)
IDA

基因相关microRNA

基因相关microRNA

可能调控 NECTIN2基因的相关microRNA：     

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因通路

基因通路

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源

基因相关服务

基因相关服务

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