Membrane mucins, such as MUC17, function in epithelial cells to provide cytoprotection, maintain luminal structure, provide signal transduction, and confer antiadhesive properties upon cancer cells that lose their apical/basal polarization.[supplied by OMIM, Apr 2004]
膜粘蛋白,如MUC17,在上皮细胞的功能,提供细胞保护作用,保持管腔结构,提供信号转导,并赋予对癌细胞附着防止属性失去其顶/底极化[由OMIM,2004年四月供应]
MUC17基因(以及对应的蛋白质)的细胞分布位置:
MUC17基因的本体(GO)信息:
名称 |
---|
Metabolism of proteins |
O-linked glycosylation |
O-linked glycosylation of mucins |
Post-translational protein modification |
Termination of O-glycan biosynthesis |
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Laryngitis | 0.00272435 | 1 | 0 | LHGDN |
Colon Carcinoma | 0.001085767 | 4 | 0 | BeFree |
Malignant tumor of colon | 0.001085767 | 4 | 0 | BeFree |
Adenoma | 0.000814326 | 3 | 0 | BeFree |
Colorectal Cancer | 0.000542884 | 2 | 0 | BeFree |
Pancreatic Neoplasm | 0.000542884 | 2 | 0 | BeFree |
Pancreatic Ductal Adenocarcinoma | 0.000542884 | 2 | 0 | BeFree |
Ovarian Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Ulcerative Colitis | 0.000542884 | 2 | 0 | BeFree |
Colorectal Carcinoma | 0.000542884 | 2 | 0 | BeFree |
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