FGF1 (fibroblast growth factor 1)
- symbol:
- FGF1
- locus group:
- protein-coding gene
- location:
- 5q31.3
- gene_family:
- Endogenous ligands
- alias symbol:
- AFGF|ECGF|ECGFA|ECGFB|HBGF1|ECGF-beta|FGF-alpha|GLIO703
- alias name:
- heparin-binding growth factor 1|en…
- entrez id:
- 2246
- ensembl gene id:
- ENSG00000113578
- ucsc gene id:
- uc003lms.5
- refseq accession:
- NM_000800
- hgnc_id:
- HGNC:3665
- approved reserved:
- 1986-01-01
FGF1（成纤维细胞生长因子1）是一种重要的生长因子，属于FGF基因家族，该家族包含22个成员，主要参与细胞增殖、分化、迁移和存活等生物学过程。FGF家族成员的共性是它们通过结合FGF受体（FGFR）并激活下游信号通路（如MAPK、PI3K-AKT等）来调控多种生理功能。FGF1是一种非糖基化蛋白，具有广泛的生物学活性，尤其在组织修复、血管生成和伤口愈合中发挥关键作用。它的主要作用位点包括内皮细胞、成纤维细胞和神经元等，通过促进这些细胞的增殖和迁移来参与组织再生。FGF1的突变可能导致其功能异常，例如失去与受体的结合能力或信号传导障碍，进而影响组织修复和血管形成，甚至与某些疾病如癌症、糖尿病和心血管疾病相关。研究表明，FGF1的过表达可能促进肿瘤血管生成和癌细胞生长，而降低表达则可能延缓伤口愈合或导致组织再生能力下降。此外，FGF1在代谢调控中也具有重要作用，例如它能够改善胰岛素敏感性，因此在糖尿病治疗中具有潜在应用价值。FGF1还与其他基因如VEGF（血管内皮生长因子）和PDGF（血小板衍生生长因子）协同作用，共同调节血管生成和组织修复。由于FGF1的多功能性，它在再生医学和疾病治疗领域备受关注，但过度激活也可能带来副作用，如促进肿瘤进展，因此其应用需谨慎调控。
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009]
由该基因编码的蛋白质是成纤维细胞生长因子（FGF）家族的一个成员。 FGF家族成员具有广泛的促有丝分裂和细胞存活的活动，并参与各种生物学过程，包括胚胎发育，细胞生长，形态发生，组织修复，肿瘤生长和侵袭。该蛋白质作为内皮细胞迁移和增殖的改性剂，以及血管生成因子。它作为用于各种体外mesoderm-和神经外胚层来源的细胞的有丝分裂原，从而被认为是参与器官发生。编码不同同种型的多个可变剪接变体已有描述。 [由RefSeq的，2009年1月提供]
正向引物序列
正向Tm值
反向引物序列
反向Tm值
评分
GTAGAACAGTGTGGACATTGC
60
GCTTTCAAGACTCTTTGCCT
59
CTCTTTAGTCTTGAAAGCGC
57
ATTAAACTTCTCGGTCAGGG
57
CTTCAACACTTCTTGAAAGCG
58
GATTAAACTTCTCGGTCAGGG
59
TTATACGGCTCACAGACACC
60
TCTCTGCATGCTTCTTGGA
59
CTCAAAGAAGGGCTTTGCC
59
CTGTGAAGGTGGTGATTTCC
59
AGAACAGTGTGGACATTGC
58
CGCTTTCAAGACTCTTTGC
58
CTCAAAGAAGGGCTTTGCC
59
TGTGAAGGTGGTGATTTCC
58
TATACGGCTCACAGACACC
59
TTCTCTGCATGCTTCTTGG
58
AGCTCTTTAGTCTTGAAAGCG
59
TAAACTTCTCGGTCAGGGC
59
TTCAACACTTCTTGAAAGCG
57
ATTAAACTTCTCGGTCAGGG
57
基因本体信息
FGF1基因（以及对应的蛋白质）的细胞分布位置：
- 质膜
- 细胞质
- 细胞外
- 高尔基体
- 囊泡
- 细胞骨架
- 内质网
- 细胞核
- 内体
- 溶酶体
- 线粒体
FGF1基因的本体（GO）信息：
GO库代码
对应的蛋白质
来源代码
GO:0005104
B5MCF4 (UniProtKB)
IEA
GO:0005576
B5MCF4 (UniProtKB)
IEA
GO:0005654
B5MCF4 (UniProtKB)
IDA
GO:0008083
B5MCF4 (UniProtKB)
IEA
GO:0008543
B5MCF4 (UniProtKB)
IEA
GO:0005104
C9JDC5 (UniProtKB)
IEA
GO:0005576
C9JDC5 (UniProtKB)
IEA
GO:0005654
C9JDC5 (UniProtKB)
IDA
GO:0008083
C9JDC5 (UniProtKB)
IEA
GO:0008543
C9JDC5 (UniProtKB)
IEA
GO:0005104
C9JUP6 (UniProtKB)
IEA
GO:0005576
C9JUP6 (UniProtKB)
IEA
GO:0008083
C9JUP6 (UniProtKB)
IEA
GO:0008543
C9JUP6 (UniProtKB)
IEA
GO:0000165
P05230 (UniProtKB)
TAS
GO:0000187
P05230 (UniProtKB)
IMP
GO:0001525
P05230 (UniProtKB)
IEA
GO:0001759
P05230 (UniProtKB)
IEA
GO:0004713
P05230 (UniProtKB)
TAS
GO:0004713
P05230 (UniProtKB)
TAS
GO:0005088
P05230 (UniProtKB)
TAS
GO:0005104
P05230 (UniProtKB)
IPI
GO:0005104
P05230 (UniProtKB)
IPI
GO:0005104
P05230 (UniProtKB)
IPI
GO:0005104
P05230 (UniProtKB)
IMP
GO:0005178
P05230 (UniProtKB)
IDA
GO:0005515
P05230 (UniProtKB)
IPI
GO:0005515
P05230 (UniProtKB)
IPI
GO:0005515
P05230 (UniProtKB)
IPI
GO:0005515
P05230 (UniProtKB)
IPI
GO:0005515
P05230 (UniProtKB)
IPI
GO:0005515
P05230 (UniProtKB)
IPI
GO:0005515
P05230 (UniProtKB)
IPI
GO:0005515
P05230 (UniProtKB)
IPI
GO:0005576
P05230 (UniProtKB)
IDA
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005576
P05230 (UniProtKB)
TAS
GO:0005578
P05230 (UniProtKB)
IEA
GO:0005615
P05230 (UniProtKB)
IDA
GO:0005654
P05230 (UniProtKB)
IDA
GO:0005730
P05230 (UniProtKB)
IEA
GO:0005829
P05230 (UniProtKB)
IDA
GO:0005938
P05230 (UniProtKB)
IEA
GO:0007165
P05230 (UniProtKB)
NAS
GO:0007275
P05230 (UniProtKB)
TAS
GO:0008083
P05230 (UniProtKB)
IDA
GO:0008201
P05230 (UniProtKB)
IMP
GO:0008201
P05230 (UniProtKB)
IDA
GO:0008283
P05230 (UniProtKB)
IEA
GO:0008284
P05230 (UniProtKB)
IGI
GO:0008284
P05230 (UniProtKB)
IGI
GO:0008284
P05230 (UniProtKB)
IGI
GO:0008284
P05230 (UniProtKB)
IGI
GO:0008284
P05230 (UniProtKB)
IMP
GO:0008284
P05230 (UniProtKB)
IMP
GO:0008284
P05230 (UniProtKB)
IGI
GO:0008284
P05230 (UniProtKB)
IGI
GO:0008543
P05230 (UniProtKB)
IPI
GO:0008543
P05230 (UniProtKB)
IGI
GO:0008543
P05230 (UniProtKB)
IGI
GO:0008543
P05230 (UniProtKB)
IGI
GO:0008543
P05230 (UniProtKB)
IGI
GO:0008543
P05230 (UniProtKB)
IMP
GO:0008543
P05230 (UniProtKB)
IDA
GO:0008543
P05230 (UniProtKB)
IGI
GO:0008543
P05230 (UniProtKB)
IGI
GO:0008543
P05230 (UniProtKB)
IGI
GO:0008543
P05230 (UniProtKB)
TAS
GO:0008543
P05230 (UniProtKB)
TAS
GO:0008543
P05230 (UniProtKB)
TAS
GO:0008543
P05230 (UniProtKB)
TAS
GO:0008543
P05230 (UniProtKB)
TAS
GO:0008543
P05230 (UniProtKB)
TAS
GO:0008543
P05230 (UniProtKB)
TAS
GO:0008543
P05230 (UniProtKB)
TAS
GO:0008543
P05230 (UniProtKB)
TAS
GO:0008543
P05230 (UniProtKB)
TAS
GO:0008543
P05230 (UniProtKB)
TAS
GO:0009653
P05230 (UniProtKB)
TAS
GO:0010595
P05230 (UniProtKB)
IMP
GO:0014066
P05230 (UniProtKB)
TAS
GO:0016303
P05230 (UniProtKB)
TAS
GO:0018108
P05230 (UniProtKB)
IEA
GO:0030154
P05230 (UniProtKB)
IEA
GO:0030324
P05230 (UniProtKB)
IEA
GO:0030335
P05230 (UniProtKB)
IMP
GO:0030335
P05230 (UniProtKB)
IDA
GO:0030544
P05230 (UniProtKB)
IEA
GO:0032148
P05230 (UniProtKB)
IMP
GO:0034605
P05230 (UniProtKB)
IDA
GO:0036092
P05230 (UniProtKB)
IEA
GO:0043406
P05230 (UniProtKB)
IDA
GO:0043547
P05230 (UniProtKB)
IEA
GO:0044548
P05230 (UniProtKB)
IPI
GO:0045542
P05230 (UniProtKB)
IDA
GO:0045766
P05230 (UniProtKB)
IDA
GO:0045944
P05230 (UniProtKB)
IDA
GO:0046854
P05230 (UniProtKB)
IEA
GO:0046934
P05230 (UniProtKB)
TAS
GO:0048015
P05230 (UniProtKB)
TAS
GO:0050679
P05230 (UniProtKB)
IEA
GO:0051781
P05230 (UniProtKB)
IDA
GO:0060681
P05230 (UniProtKB)
IDA
GO:0070374
P05230 (UniProtKB)
IC
GO:0072163
P05230 (UniProtKB)
IDA
GO:1901509
P05230 (UniProtKB)
IMP
GO:1902533
P05230 (UniProtKB)
IDA
GO:1903672
P05230 (UniProtKB)
IMP
GO:2000544
P05230 (UniProtKB)
IDA
| 名称 |
|---|
| 4014 Ras signaling pathway [PATH:hsa04014] |
| 4015 Rap1 signaling pathway [PATH:hsa04015] |
| 4010 MAPK signaling pathway [PATH:hsa04010] |
| 4390 Hippo signaling pathway [PATH:hsa04390] |
| 4151 PI3K-Akt signaling pathway [PATH:hsa04151] |
| 4810 Regulation of actin cytoskeleton [PATH:hsa04810] |
| 5200 Pathways in cancer [PATH:hsa05200] |
| 5218 Melanoma [PATH:hsa05218] |
| 名称 |
|---|
| Activated point mutants of FGFR2 |
| Adaptive Immune System |
| Constitutive Signaling by Aberrant PI3K in Cancer |
| DAP12 interactions |
| DAP12 signaling |
| Disease |
| Diseases of signal transduction |
| Downstream signal transduction |
| Downstream signaling events of B Cell Receptor (BCR) |
| Downstream signaling of activated FGFR1 |
| Downstream signaling of activated FGFR2 |
| Downstream signaling of activated FGFR3 |
| Downstream signaling of activated FGFR4 |
| Fc epsilon receptor (FCERI) signaling |
| FGFR1 ligand binding and activation |
| FGFR1 mutant receptor activation |
| FGFR1b ligand binding and activation |
| FGFR1c ligand binding and activation |
| FGFR2 ligand binding and activation |
| FGFR2 mutant receptor activation |
| FGFR2b ligand binding and activation |
| FGFR2c ligand binding and activation |
| FGFR3 ligand binding and activation |
| FGFR3 mutant receptor activation |
| FGFR3b ligand binding and activation |
| FGFR3c ligand binding and activation |
| FGFR4 ligand binding and activation |
| FRS-mediated FGFR1 signaling |
| FRS-mediated FGFR2 signaling |
| FRS-mediated FGFR3 signaling |
| FRS2-mediated FGFR4 signaling |
| GAB1 signalosome |
| IGF1R signaling cascade |
| Immune System |
| Innate Immune System |
| Insulin receptor signalling cascade |
| IRS-mediated signalling |
| IRS-related events |
| IRS-related events triggered by IGF1R |
| Negative regulation of FGFR1 signaling |
| Negative regulation of FGFR2 signaling |
| Negative regulation of FGFR3 signaling |
| Negative regulation of FGFR4 signaling |
| NGF signalling via TRKA from the plasma membrane |
| Phospholipase C-mediated cascade; FGFR2 |
| Phospholipase C-mediated cascade; FGFR3 |
| Phospholipase C-mediated cascade; FGFR4 |
| Phospholipase C-mediated cascade: FGFR1 |
| PI-3K cascade:FGFR1 |
| PI-3K cascade:FGFR2 |
| PI-3K cascade:FGFR3 |
| PI-3K cascade:FGFR4 |
| PI3K Cascade |
| PI3K events in ERBB2 signaling |
| PI3K events in ERBB4 signaling |
| PI3K/AKT activation |
| PI3K/AKT Signaling in Cancer |
| PIP3 activates AKT signaling |
| Role of LAT2/NTAL/LAB on calcium mobilization |
| SHC-mediated cascade:FGFR1 |
| SHC-mediated cascade:FGFR2 |
| SHC-mediated cascade:FGFR3 |
| SHC-mediated cascade:FGFR4 |
| Signal Transduction |
| Signaling by activated point mutants of FGFR1 |
| Signaling by activated point mutants of FGFR3 |
| Signaling by EGFR |
| Signaling by ERBB2 |
| Signaling by ERBB4 |
| Signaling by FGFR |
| Signaling by FGFR in disease |
| Signaling by FGFR1 |
| Signaling by FGFR1 in disease |
| Signaling by FGFR1 mutants |
| Signaling by FGFR2 |
| Signaling by FGFR2 in disease |
| Signaling by FGFR2 mutants |
| Signaling by FGFR3 |
| Signaling by FGFR3 in disease |
| Signaling by FGFR3 mutants |
| Signaling by FGFR4 |
| Signaling by FGFR4 in disease |
| Signaling by FGFR4 mutants |
| Signaling by Insulin receptor |
| Signaling by PDGF |
| Signaling by SCF-KIT |
| Signaling by the B Cell Receptor (BCR) |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) |
| Signalling by NGF |
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Mesothelioma | 0.120542884 | 3 | 0 | BeFree_CTD_human |
| Myocardial Ischemia | 0.120271442 | 2 | 0 | BeFree_CTD_human |
| Pulmonary Fibrosis | 0.120271442 | 2 | 0 | BeFree_CTD_human |
| leukemia | 0.120271442 | 2 | 0 | BeFree_CTD_human |
| Hypotension | 0.12 | 1 | 0 | CTD_human |
| Weight Gain | 0.12 | 1 | 0 | CTD_human |
| Cardiac Hypertrophy | 0.12 | 1 | 1 | GWASCAT |
| Reperfusion Injury | 0.08 | 1 | 0 | RGD |
| Brain Ischemia | 0.08 | 1 | 0 | RGD |
| Alzheimer's Disease | 0.010096888 | 4 | 0 | BeFree_GAD_LHGDN |
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