FCRL5 (Fc receptor like 5)
- symbol:
- FCRL5
- locus group:
- protein-coding gene
- location:
- 1q23.1
- gene_family:
- CD molecules|Immunoglobulin-like domain containing
- alias symbol:
- FCRH5|IRTA2|BXMAS1|CD307e
- alias name:
- None
- entrez id:
- 83416
- ensembl gene id:
- ENSG00000143297
- ucsc gene id:
- uc001fqu.3
- refseq accession:
- NM_031281
- hgnc_id:
- HGNC:18508
- approved reserved:
- 2005-03-22
This gene encodes a member of the immunoglobulin receptor superfamily and the Fc-receptor like family. This gene and several other Fc receptor-like gene members are clustered on the long arm of chromosome 1. The encoded protein is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains. This gene is implicated in B cell development and lymphomagenesis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010]
该基因编码的免疫球蛋白受体超家族与FC-样受体家族中的一员。此基因和其他一些Fc受体样基因成员1号染色体上的编码的蛋白质的长臂聚集是单遍的I型膜蛋白，并且包含8免疫球蛋白样C2型结构域。该基因在B细胞发育和淋巴瘤牵连。编码不同同种型的可变剪接转录物变体也已确定。 [由RefSeq的，2010年9月提供]
基因本体信息
FCRL5基因（以及对应的蛋白质）的细胞分布位置：
- 质膜
- 细胞质
- 细胞外
- 高尔基体
- 囊泡
- 细胞骨架
- 内质网
- 细胞核
- 内体
- 溶酶体
- 线粒体
FCRL5基因的本体（GO）信息：
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Hairy Cell Leukemia | 0.005720142 | 2 | 0 | BeFree_LHGDN |
| Chronic Lymphocytic Leukemia | 0.003267234 | 2 | 0 | BeFree_LHGDN |
| Lymphoma | 0.002995792 | 1 | 0 | BeFree_LHGDN |
| Graves Disease | 0.002638474 | 1 | 0 | BeFree_GAD |
| Ankylosing spondylitis | 0.002638474 | 1 | 0 | BeFree_GAD |
| Leukemogenesis | 0.000271442 | 1 | 0 | BeFree |
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