FATE1 (fetal and adult testis expressed 1)

基因基本信息

基因基本信息

symbol:
FATE1
locus group:
protein-coding gene
location:
Xq28
gene_family:
alias symbol:
FATE|CT43
alias name:
cancer/testis antigen 43
entrez id:
89885
ensembl gene id:
ENSG00000147378
ucsc gene id:
uc004fex.4
refseq accession:
NM_033085
hgnc_id:
HGNC:24683
approved reserved:
2004-09-01

基因染色体位置

基因染色体位置

Xq28
基因染色体位置图

基因简述

基因简述

This gene encodes a cancer-testis antigen that is highly expressed in hepatocellular carcinomas and other tumors and weakly expressed in normal tissues except testis. The protein is strongly expressed in spermatogonia, primary spermatocytes, and Sertoli cells in seminiferous tubules. This protein may have a role in the control of early testicular differentiation and cell proliferation. [provided by RefSeq, Jan 2010]

该基因编码是肝癌等肿瘤高表达，除了睾丸正常组织弱表达癌睾丸抗原。该蛋白在精原细胞，初级精母细胞，并在细精管支持细胞中强烈表达。这种蛋白可能在早期睾丸分化和细??胞增殖的控制作用。 [由RefSeq的，2010年1月提供]

OMIM数据库中对CCND1基因的介绍     Wikipedia数据库中对CCND1基因的介绍

基因序列

基因序列

CCND1基因的碱基序列：[NCBI]
Loading Gene Browser...

基因突变

基因突变

FATE1基因的碱基突变：           仅显示部分snp
rs781494439       rs781251878       rs781196707       rs780885809       rs780862186       rs780796397       rs780857408       rs780745268       rs779571906       rs779541869       rs779349889       rs779068306       rs779142458       rs779034401       rs778803221       rs778394151       rs778577078      

基因表达

基因表达

FATE1基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向Tm值
反向引物序列
反向Tm值
评分
GAGATGGAAATGTCCCTGG
58
CCATCATTTCTGCTATCACCA
58
ATTATGATCGCAACCCAGG
58
TCTCATGACTTCCATCTCCA
58
GAGATGGAAATGTCCCTGG
58
CCATCATTTCTGCTATCACCA
58
AGATGGAAATGTCCCTGGC
60
TCCATCATTTCTGCTATCACCA
60
TTATGATCGCAACCCAGGG
60
TCTCATGACTTCCATCTCCAG
59
AGATGGAAATGTCCCTGGC
60
TCCATCATTTCTGCTATCACCA
60
AGATGGAAATGTCCCTGGC
60
CCATCATTTCTGCTATCACCAG
59
AGATGGAAATGTCCCTGGC
60
CCATCATTTCTGCTATCACCAG
59
ATTATGATCGCAACCCAGG
58
CTCATGACTTCCATCTCCAG
58

转录因子

转录因子

      尚未收录相关数据

基因本体信息

FATE1基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 质膜
  • 细胞质
  • 细胞外
  • 高尔基体
  • 囊泡
  • 细胞骨架
  • 内质网
  • 细胞核
  • 内体
  • 溶酶体
  • 线粒体

FATE1基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005515
Q969F0 (UniProtKB)
IPI
GO:0005783
Q969F0 (UniProtKB)
IDA
GO:0016021
Q969F0 (UniProtKB)
IEA

基因相关microRNA

基因相关microRNA

可能调控 FATE1基因的相关microRNA：     

基因相互作用关系

基因相互作用关系

MINT

BioGrid

IntAct

mentha

String

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因通路

基因通路

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Liver carcinoma 0.12 1 0 CTD_human
Biliary Tract Cancer 0.000271442 1 0 BeFree
Malignant neoplasm of testis 0.000271442 1 0 BeFree
Multiple Sclerosis 0.000271442 1 0 BeFree
Breast Carcinoma 0.000271442 1 0 BeFree
Male infertility 0.000271442 1 0 BeFree
Malignant neoplasm of breast 0.000271442 1 0 BeFree
Niemann-Pick Disease, Type C 0.000271442 1 0 BeFree
Irritable Bowel Syndrome 0.000271442 1 0 BeFree
Ichthyosis Bullosa of Siemens 0.000271442 1 0 BeFree

基因相关服务

基因相关服务

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