DLC1 (DLC1 Rho GTPase activating protein)

基因基本信息

基因基本信息

symbol:
DLC1
locus group:
protein-coding gene
location:
8p22
gene_family:
Rho GTPase activating proteins|StAR-related lipid transfer (START) domain containing
alias symbol:
HP|ARHGAP7|STARD12|DLC-1|p122-RhoGAP
alias name:
StAR-related lipid transfer (START…
entrez id:
10395
ensembl gene id:
ENSG00000164741
ucsc gene id:
uc003wwm.3
refseq accession:
NM_182643|NM_006094
hgnc_id:
HGNC:2897
approved reserved:
1999-06-17

基因染色体位置

基因染色体位置

8p22
基因染色体位置图

基因序列

基因序列

CCND1基因的碱基序列：[NCBI]
Loading Gene Browser...

基因突变

基因突变

DLC1基因的碱基突变：           仅显示部分snp
rs2027       rs2377       rs17514       rs167042       rs167043       rs167044       rs172322       rs172323       rs185977       rs188299       rs192627       rs209072       rs289510       rs289511       rs289512       rs289513       rs289514      

基因表达

基因表达

DLC1基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向Tm值
反向引物序列
反向Tm值
评分
AGATAACCAAGTCAGACTTCG
58
AAAGCCAGAGAATCTGTGC
58
ACATGTGATTAACCAGATAGGC
58
TGGAAGGCTCTAAAGAAACAG
58
AATACGATCAAGATGGAGCCT
59
CATTTCACCACCTCTAGTCAG
58
TCGATATTTCCTTGGTCAAGAG
58
TCTGAATCGTCACTCTGCA
59
CAGACTACAAGGACCGGAG
59
TTCTGAAGAGCCCAACCTG
60
TCTTCTGACACTGAGTCCA
58
TTGAATAGCCGTAGTCTTGG
57
ATAAGAAGGTGAGCGAAGGA
59
TTAAGATTTCCTCTGGCACAG
58
CAGTAGCCAATTCTGGAACC
59
TTGGCTTCAATTTCAGCCT
58
CAGTATGGCACCTCATCCT
59
GGGTAAATTAGTCCTCCAGGT
59
TTAACCAGGTGGTGAAATGAC
59
GCTTCTCTTTCTGATAGCTACAG
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

DLC1基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 质膜
  • 细胞质
  • 细胞外
  • 高尔基体
  • 囊泡
  • 细胞骨架
  • 内质网
  • 细胞核
  • 内体
  • 溶酶体
  • 线粒体

DLC1基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0001843
Q96QB1 (UniProtKB)
ISS
GO:0003007
Q96QB1 (UniProtKB)
ISS
GO:0005096
Q96QB1 (UniProtKB)
IMP
GO:0005096
Q96QB1 (UniProtKB)
IDA
GO:0005096
Q96QB1 (UniProtKB)
TAS
GO:0005515
Q96QB1 (UniProtKB)
IPI
GO:0005515
Q96QB1 (UniProtKB)
IPI
GO:0005515
Q96QB1 (UniProtKB)
IPI
GO:0005515
Q96QB1 (UniProtKB)
IPI
GO:0005515
Q96QB1 (UniProtKB)
IPI
GO:0005634
Q96QB1 (UniProtKB)
IDA
GO:0005737
Q96QB1 (UniProtKB)
IDA
GO:0005737
Q96QB1 (UniProtKB)
IDA
GO:0005829
Q96QB1 (UniProtKB)
IDA
GO:0005829
Q96QB1 (UniProtKB)
TAS
GO:0005901
Q96QB1 (UniProtKB)
IDA
GO:0005925
Q96QB1 (UniProtKB)
IDA
GO:0005925
Q96QB1 (UniProtKB)
IDA
GO:0006915
Q96QB1 (UniProtKB)
IDA
GO:0006919
Q96QB1 (UniProtKB)
IDA
GO:0007165
Q96QB1 (UniProtKB)
IEA
GO:0008285
Q96QB1 (UniProtKB)
IDA
GO:0008285
Q96QB1 (UniProtKB)
IMP
GO:0008285
Q96QB1 (UniProtKB)
IDA
GO:0008289
Q96QB1 (UniProtKB)
IEA
GO:0008360
Q96QB1 (UniProtKB)
IMP
GO:0021575
Q96QB1 (UniProtKB)
ISS
GO:0030036
Q96QB1 (UniProtKB)
ISS
GO:0030336
Q96QB1 (UniProtKB)
IMP
GO:0030336
Q96QB1 (UniProtKB)
IMP
GO:0030336
Q96QB1 (UniProtKB)
IDA
GO:0030336
Q96QB1 (UniProtKB)
IDA
GO:0030864
Q96QB1 (UniProtKB)
IDA
GO:0030900
Q96QB1 (UniProtKB)
ISS
GO:0032587
Q96QB1 (UniProtKB)
IDA
GO:0032956
Q96QB1 (UniProtKB)
IMP
GO:0035024
Q96QB1 (UniProtKB)
IMP
GO:0035307
Q96QB1 (UniProtKB)
IDA
GO:0042169
Q96QB1 (UniProtKB)
IPI
GO:0042169
Q96QB1 (UniProtKB)
IPI
GO:0042169
Q96QB1 (UniProtKB)
IPI
GO:0042169
Q96QB1 (UniProtKB)
IPI
GO:0043547
Q96QB1 (UniProtKB)
IEA
GO:0048041
Q96QB1 (UniProtKB)
ISS
GO:0051056
Q96QB1 (UniProtKB)
TAS
GO:0051497
Q96QB1 (UniProtKB)
IDA
GO:0051895
Q96QB1 (UniProtKB)
IDA
GO:1900119
Q96QB1 (UniProtKB)
IDA
GO:0005096
Q96QB1 (UniProtKB)
IDA

基因相关microRNA

基因相关microRNA

可能调控 DLC1基因的相关microRNA：     

基因相互作用关系

基因相互作用关系

Reactome

MINT

BioGrid

IntAct

mentha

String

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因通路

基因通路

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Stomach Neoplasms 0.12272435 2 0 CTD_human_LHGDN
Colon Carcinoma 0.121900093 7 1 BeFree_CLINVAR
ovarian neoplasm 0.120271442 2 0 BeFree_CTD_human
Liver carcinoma 0.016240362 21 0 BeFree_GAD_LHGDN
Mammary Neoplasms 0.006534468 5 0 BeFree_LHGDN
Liver neoplasms 0.006448592 7 0 BeFree_GAD_LHGDN
Lung Neoplasms 0.005720142 3 0 BeFree_LHGDN
Carcinogenesis 0.00434307 16 0 BeFree
Malignant neoplasm of liver 0.003800186 14 0 BeFree
Liver and Intrahepatic Biliary Tract Carcinoma 0.003800186 14 0 BeFree

基因相关服务

基因相关服务

联系方式

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