DCR (Down syndrome chromosome region)
- symbol:
- DCR
- locus group:
- other
- location:
- 21q22.3
- gene_family:
- alias symbol:
- DSCR
- alias name:
- None
- entrez id:
- 1637
- ensembl gene id:
- None
- ucsc gene id:
- None
- refseq accession:
- None
- hgnc_id:
- HGNC:2708
- approved reserved:
- 1990-09-10
Down syndrome, the most frequent form of mental retardation caused by a microscopically demonstrable chromosomal aberration, is characterized by well-defined and distinctive phenotypic features and natural history. It is caused by triplicate state (trisomy) of all or a critical portion of chromosome 21.[supplied by OMIM, Apr 2005]
唐氏综合症，引起的微观上可证明染色体畸变精神发育迟缓的最常见的形式中，其特征在于明确定义和独特的表型特征和自然历史。它是由所有的一式三份的状态（三体）或21号染色体的关键部分引起[由OMIM，2005年4月供给]
基因本体信息
DCR基因（以及对应的蛋白质）的细胞分布位置：
- 质膜
- 细胞质
- 细胞外
- 高尔基体
- 囊泡
- 细胞骨架
- 内质网
- 细胞核
- 内体
- 溶酶体
- 线粒体
DCR基因的本体（GO）信息：
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Down Syndrome | 0.121085767 | 4 | 0 | BeFree_CTD_human |
| Mental Retardation | 0.000542884 | 2 | 0 | BeFree |
| Dysmorphic features | 0.000271442 | 1 | 0 | BeFree |
| Cerebral Infarction | 0.000271442 | 1 | 0 | BeFree |
| Abnormal dermatoglyphic pattern | 0.000271442 | 1 | 0 | BeFree |
| Sepsis | 0.000271442 | 1 | 0 | BeFree |
| Septicemia | 0.000271442 | 1 | 0 | BeFree |
| Cerebrovascular accident | 0.000271442 | 1 | 0 | BeFree |
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