CXADR (CXADR Ig-like cell adhesion molecule)

基因基本信息

基因基本信息

symbol:
CXADR
locus group:
protein-coding gene
location:
21q21.1
gene_family:
V-set domain containing|Immunoglobulin-like domain containing
alias symbol:
CAR
alias name:
None
entrez id:
1525
ensembl gene id:
ENSG00000154639
ucsc gene id:
uc002yki.4
refseq accession:
NM_001207063
hgnc_id:
HGNC:2559
approved reserved:
1998-03-24

基因染色体位置

基因染色体位置

21q21.1
基因染色体位置图

基因简述

基因简述

The protein encoded by this gene is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Several transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene are found on chromosomes 15, 18, and 21. [provided by RefSeq, May 2011]

由该基因编码的蛋白质为B组柯萨奇病毒和亚群C腺病毒I型膜受体。已发现该基因编码不同亚型的几个抄本变形。该基因的假基因在染色体上15日，18位和21 [由RefSeq的，2011年5月提供]

OMIM数据库中对CCND1基因的介绍     Wikipedia数据库中对CCND1基因的介绍

基因序列

基因序列

CCND1基因的碱基序列：[NCBI]
Loading Gene Browser...

基因突变

基因突变

CXADR基因的碱基突变：           仅显示部分snp
rs15459       rs928248       rs2824386       rs2824387       rs2824388       rs2824389       rs2824390       rs2824391       rs2824392       rs2824393       rs2824394       rs2824395       rs2824396       rs2824397       rs2824398       rs2824399       rs3737411      

基因表达

基因表达

CXADR基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向Tm值
反向引物序列
反向Tm值
评分
GAGTAGTGGATTTCGCCAG
58
ATTTGCATGGCAGATAGGC
58
TGCGGAGTAGTGGATTTCG
59
TGGCAGATAGGCAGTTTCC
59
GGAGTAGTGGATTTCGCCA
59
TGGCAGATAGGCAGTTTCC
59

转录因子

转录因子

转录因子
影响基因
影响类型
参考文献链接（PubMed）
SNAI1
CXADR
Repression
10487759
SNAI2
CXADR
Repression
10487759
SP1
CXADR
Unknown
22190856
ZEB1
CXADR
Repression
10487759
ZEB2
CXADR
Repression
10487759

基因本体信息

CXADR基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 质膜
  • 细胞质
  • 细胞外
  • 高尔基体
  • 囊泡
  • 细胞骨架
  • 内质网
  • 细胞核
  • 内体
  • 溶酶体
  • 线粒体

CXADR基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0001618
P78310 (UniProtKB)
IEA
GO:0001669
P78310 (UniProtKB)
ISS
GO:0005102
P78310 (UniProtKB)
IPI
GO:0005102
P78310 (UniProtKB)
IPI
GO:0005102
P78310 (UniProtKB)
IPI
GO:0005102
P78310 (UniProtKB)
IPI
GO:0005102
P78310 (UniProtKB)
IPI
GO:0005102
P78310 (UniProtKB)
IPI
GO:0005178
P78310 (UniProtKB)
IPI
GO:0005515
P78310 (UniProtKB)
IPI
GO:0005515
P78310 (UniProtKB)
IPI
GO:0005576
P78310 (UniProtKB)
IEA
GO:0005615
P78310 (UniProtKB)
IDA
GO:0005615
P78310 (UniProtKB)
IDA
GO:0005615
P78310 (UniProtKB)
IDA
GO:0005654
P78310 (UniProtKB)
IDA
GO:0005737
P78310 (UniProtKB)
IDA
GO:0005886
P78310 (UniProtKB)
IDA
GO:0005886
P78310 (UniProtKB)
IDA
GO:0005886
P78310 (UniProtKB)
IDA
GO:0005886
P78310 (UniProtKB)
TAS
GO:0005887
P78310 (UniProtKB)
NAS
GO:0005911
P78310 (UniProtKB)
IDA
GO:0005911
P78310 (UniProtKB)
IDA
GO:0005912
P78310 (UniProtKB)
IDA
GO:0005923
P78310 (UniProtKB)
IDA
GO:0005923
P78310 (UniProtKB)
IDA
GO:0005923
P78310 (UniProtKB)
IDA
GO:0007005
P78310 (UniProtKB)
ISS
GO:0007157
P78310 (UniProtKB)
IDA
GO:0007157
P78310 (UniProtKB)
IDA
GO:0007507
P78310 (UniProtKB)
ISS
GO:0008013
P78310 (UniProtKB)
IPI
GO:0008354
P78310 (UniProtKB)
ISS
GO:0009986
P78310 (UniProtKB)
IBA
GO:0010669
P78310 (UniProtKB)
IMP
GO:0014704
P78310 (UniProtKB)
IDA
GO:0014704
P78310 (UniProtKB)
IDA
GO:0016323
P78310 (UniProtKB)
IDA
GO:0016323
P78310 (UniProtKB)
IDA
GO:0016327
P78310 (UniProtKB)
IDA
GO:0030054
P78310 (UniProtKB)
IDA
GO:0030165
P78310 (UniProtKB)
IPI
GO:0030175
P78310 (UniProtKB)
ISS
GO:0030426
P78310 (UniProtKB)
ISS
GO:0030593
P78310 (UniProtKB)
IMP
GO:0031532
P78310 (UniProtKB)
IDA
GO:0031594
P78310 (UniProtKB)
IDA
GO:0034109
P78310 (UniProtKB)
IDA
GO:0042802
P78310 (UniProtKB)
IDA
GO:0043005
P78310 (UniProtKB)
ISS
GO:0043234
P78310 (UniProtKB)
IDA
GO:0044297
P78310 (UniProtKB)
ISS
GO:0045121
P78310 (UniProtKB)
IDA
GO:0045216
P78310 (UniProtKB)
ISS
GO:0046629
P78310 (UniProtKB)
ISS
GO:0046718
P78310 (UniProtKB)
IEA
GO:0048739
P78310 (UniProtKB)
ISS
GO:0050776
P78310 (UniProtKB)
TAS
GO:0050839
P78310 (UniProtKB)
IPI
GO:0050839
P78310 (UniProtKB)
IPI
GO:0050900
P78310 (UniProtKB)
TAS
GO:0051607
P78310 (UniProtKB)
IDA
GO:0051607
P78310 (UniProtKB)
IDA
GO:0051607
P78310 (UniProtKB)
IDA
GO:0070633
P78310 (UniProtKB)
IMP
GO:0071253
P78310 (UniProtKB)
ISS
GO:0086067
P78310 (UniProtKB)
ISS

基因相关microRNA

基因相关microRNA

可能调控 CXADR基因的相关microRNA：     

基因相互作用关系

基因相互作用关系

Reactome

BioGrid

IntAct

mentha

String

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因通路

基因通路

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Infection 0.008173051 3 0 LHGDN
Cardiomyopathy, Dilated 0.006448592 6 0 BeFree_GAD_LHGDN
Adenovirus Infections 0.004895885 9 0 BeFree_LHGDN
Lung Neoplasms 0.002995792 2 0 BeFree_LHGDN
Endometrial Neoplasms 0.00272435 1 0 LHGDN
Mammary Neoplasms 0.00272435 1 0 LHGDN
Swine Vesicular Disease 0.00272435 1 0 LHGDN
Colonic Neoplasms 0.00272435 1 0 LHGDN
ovarian neoplasm 0.00272435 1 0 LHGDN
Adenocarcinoma 0.00272435 1 0 LHGDN

基因相关服务

基因相关服务

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