CLEC4C (C-type lectin domain family 4 member C)
- symbol:
- CLEC4C
- locus group:
- protein-coding gene
- location:
- 12p13.31
- gene_family:
- CD molecules|C-type lectin domain family
- alias symbol:
- HECL|DLEC|BDCA2|CD303
- alias name:
- None
- entrez id:
- 170482
- ensembl gene id:
- ENSG00000198178
- ucsc gene id:
- uc001qth.1
- refseq accession:
- NM_203503
- hgnc_id:
- HGNC:13258
- approved reserved:
- 2000-12-21
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in dendritic cell function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
该基因编码超家族的C-型凝集素/ C-型凝集素样结构域（CTL / CTLD）的成员。这家人共享一个共同的蛋白折叠，并有不同的功能，例如细胞粘附，细胞 - 细胞信号传导，糖蛋白周转和角色在炎症和免疫反应的成员。所编码的2型跨膜蛋白可能参与树突细胞功能的作用。编码不同的两种亚型变种成绩单已经确定了这个基因。 [由RefSeq的，2008年7月提供]
基因本体信息
CLEC4C基因（以及对应的蛋白质）的细胞分布位置：
- 质膜
- 细胞质
- 细胞外
- 高尔基体
- 囊泡
- 细胞骨架
- 内质网
- 细胞核
- 内体
- 溶酶体
- 线粒体
CLEC4C基因的本体（GO）信息：
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Lupus Erythematosus, Systemic | 0.00272435 | 1 | 0 | LHGDN |
| Nasopharyngeal carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Tuberculosis | 0.000271442 | 1 | 0 | BeFree |
| Nasal Polyps | 0.000271442 | 1 | 0 | BeFree |
| Blastic plasmacytoid dendritic cell neoplasm | 0.000271442 | 1 | 0 | BeFree |
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