CHD1L (chromodomain helicase DNA binding protein 1 like)

基因基本信息

基因基本信息

symbol:
CHD1L
locus group:
protein-coding gene
location:
1q21.1
gene_family:
alias symbol:
ALC1
alias name:
amplified in liver cancer 1
entrez id:
9557
ensembl gene id:
ENSG00000131778
ucsc gene id:
uc001epm.6
refseq accession:
NM_004284
hgnc_id:
HGNC:1916
approved reserved:
1999-05-28

基因染色体位置

基因染色体位置

1q21.1
基因染色体位置图

基因简述

基因简述

This gene encodes a DNA helicase protein involved in DNA repair. The protein converts ATP to add poly(ADP-ribose) as it regulates chromatin relaxation following DNA damage. Several alternatively spliced transcripts variants have been described for this gene. [provided by RefSeq, Jan 2012]

None

OMIM数据库中对CCND1基因的介绍     Wikipedia数据库中对CCND1基因的介绍

基因序列

基因序列

CCND1基因的碱基序列：[NCBI]
Loading Gene Browser...

基因突变

基因突变

CHD1L基因的碱基突变：           仅显示部分snp
rs2452       rs6537       rs6538       rs953087       rs953088       rs1142792       rs1890036       rs1890037       rs1890038       rs1890040       rs1890041       rs1890042       rs1890043       rs1932978       rs1999820       rs2275249       rs2275250      

基因表达

基因表达

CHD1L基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向Tm值
反向引物序列
反向Tm值
评分
CTAGCATTCCTGTATTCTGGG
58
TAGCTGTAGCCTCTGTAATCC
59
CTTCATACTGAGGGCCGAG
59
TAGGTGAATCCCTGTCAGC
58
GAGTACTAGGGCAGGTGAG
59
ATGACAGTTTGGACAGGCT
59
AATAAAGGCAGTGTTCTCATCC
58
CTCCAGCTCTTCTGGACTC
59
TGAGTCAGCAAGTGAACTG
58
GGAAGCTCTGTAGCTACCT
58
ATTACAGAGGCTACAGCTATGAG
59
TGTCCAAAGTTCTTAATGGCC
58
CTTCATACTGAGGGCCGAG
60
ACACTCCAAGGGAATCTGTC
60
AAGACCTGCCAGATTTGCT
60
CCTGTTTCAGGTCTTGCTG
59
ATTCACCTACGCTCTTACCA
59
TTTAATCTTCCTGGCAGGTC
58
AGACCTGCCAGACTATTGC
60
AGGGACAAAGAATCAGAAATGG
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

CHD1L基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 质膜
  • 细胞质
  • 细胞外
  • 高尔基体
  • 囊泡
  • 细胞骨架
  • 内质网
  • 细胞核
  • 内体
  • 溶酶体
  • 线粒体

CHD1L基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0003676
A0A087WTM4 (UniProtKB)
IEA
GO:0005524
A0A087WTM4 (UniProtKB)
IEA
GO:0008026
A0A087WTM4 (UniProtKB)
IEA
GO:0003676
A0A0A0MSH9 (UniProtKB)
IEA
GO:0005524
A0A0A0MSH9 (UniProtKB)
IEA
GO:0008026
A0A0A0MSH9 (UniProtKB)
IEA
GO:0000166
Q86WJ1 (UniProtKB)
IDA
GO:0000717
Q86WJ1 (UniProtKB)
TAS
GO:0003676
Q86WJ1 (UniProtKB)
IEA
GO:0004003
Q86WJ1 (UniProtKB)
TAS
GO:0005515
Q86WJ1 (UniProtKB)
IPI
GO:0005524
Q86WJ1 (UniProtKB)
IEA
GO:0005634
Q86WJ1 (UniProtKB)
IDA
GO:0005654
Q86WJ1 (UniProtKB)
IDA
GO:0005654
Q86WJ1 (UniProtKB)
TAS
GO:0005654
Q86WJ1 (UniProtKB)
TAS
GO:0005654
Q86WJ1 (UniProtKB)
TAS
GO:0005654
Q86WJ1 (UniProtKB)
TAS
GO:0005654
Q86WJ1 (UniProtKB)
TAS
GO:0005654
Q86WJ1 (UniProtKB)
TAS
GO:0005654
Q86WJ1 (UniProtKB)
TAS
GO:0005654
Q86WJ1 (UniProtKB)
TAS
GO:0005654
Q86WJ1 (UniProtKB)
TAS
GO:0005737
Q86WJ1 (UniProtKB)
IDA
GO:0005886
Q86WJ1 (UniProtKB)
IDA
GO:0006281
Q86WJ1 (UniProtKB)
TAS
GO:0006293
Q86WJ1 (UniProtKB)
TAS
GO:0006294
Q86WJ1 (UniProtKB)
TAS
GO:0006295
Q86WJ1 (UniProtKB)
TAS
GO:0006296
Q86WJ1 (UniProtKB)
TAS
GO:0006338
Q86WJ1 (UniProtKB)
IDA
GO:0006974
Q86WJ1 (UniProtKB)
IDA
GO:0016887
Q86WJ1 (UniProtKB)
IMP
GO:0033683
Q86WJ1 (UniProtKB)
TAS
GO:0070911
Q86WJ1 (UniProtKB)
TAS

基因相关microRNA

基因相关microRNA

可能调控 CHD1L基因的相关microRNA：     

基因相互作用关系

基因相互作用关系

MINT

BioGrid

IntAct

mentha

String

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因通路

基因通路

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Substance-Related Disorders 0.12 1 0 CTD_human
Liver carcinoma 0.002442977 9 0 BeFree
Hypertrophic Cardiomyopathy 0.000814326 3 0 BeFree
Carcinogenesis 0.000542884 2 0 BeFree
Neoplasm Metastasis 0.000542884 2 0 BeFree
Nodule 0.000271442 1 0 BeFree
Invasive breast carcinoma 0.000271442 1 0 BeFree
Congenital Abnormality 0.000271442 1 0 BeFree
Solid tumour 0.000271442 1 0 BeFree
Breast Carcinoma 0.000271442 1 0 BeFree

基因相关服务

基因相关服务

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