This gene represents naturally-occurring RNAs transcribed in antisense to CDR1 (cerebellar degeneration-related protein 1, 34kDa; GeneID:1038), some of which may be circular rather than linear. Antisense circular RNAs bind microRNAs such as miR-7, acting as a sponge for these molecules and preventing them from interacting with target transcripts. The circular RNA produced by this locus is down-regulated by miR-671, which also decreases levels of the CDR1 transcript. No RefSeq transcript is created for the circular RNA. [provided by RefSeq, Jul 2014]
该基因代表天然存在的反义转录为CDR1的RNA(小脑变性相关蛋白1,34kDa; GeneID:1038),其中的一些可以是圆形的,而不是线性的。反义RNA的圆??形微RNA绑定等的miR-7,作为这些分子的海绵,防止他们与目标成绩单互动。通过该位点所产生的环状RNA是下调受miR-671,这也降低了CDR1转录物的水平。没有的RefSeq转录为RNA圆形创建。 [由RefSeq的,2014年7月提供]
CDR1-AS基因(以及对应的蛋白质)的细胞分布位置:
CDR1-AS基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Malignant neoplasm of prostate | 0.000271442 | 1 | 0 | BeFree |
Carcinogenesis | 0.000271442 | 1 | 0 | BeFree |
Prostate carcinoma | 0.000271442 | 1 | 0 | BeFree |
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