CCAR2 (cell cycle and apoptosis regulator 2)

基因基本信息

基因基本信息

symbol:
CCAR2
locus group:
protein-coding gene
location:
8p21.3
gene_family:
alias symbol:
DBC-1|DBC1|NET35
alias name:
deleted in breast cancer 1
entrez id:
57805
ensembl gene id:
ENSG00000158941
ucsc gene id:
None
refseq accession:
NM_021174
hgnc_id:
HGNC:23360
approved reserved:
2004-11-08

基因染色体位置

基因染色体位置

8p21.3
基因染色体位置图

基因序列

基因序列

CCND1基因的碱基序列：[NCBI]
Loading Gene Browser...

基因突变

基因突变

CCAR2基因的碱基突变：           仅显示部分snp
rs1869       rs1059590       rs1059592       rs1059599       rs1545837       rs3087518       rs3208240       rs13439363       rs13439369       rs13439542       rs33937830       rs74973186       rs113091101       rs116253013       rs117753515       rs140501059       rs142412882      

基因表达

基因表达

CCAR2基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向Tm值
反向引物序列
反向Tm值
评分
CGCTTATAGTTCGAAGGTACTG
59
TCATCCACAAAGAGCATGC
59
CGCTTATAGTTCGAAGGTACTG
59
TCATCCACAAAGAGCATGC
59
TCTTCCAAACATCCCACAC
58
TCATAGTCATCACTTCGGC
57
CCATCAAAGAGGAGGTGGT
59
AAAGCCCATCCTCCTTCAG
59
AACACAAAGCCTTGGTGTC
59
GGTTATGGCTCTCCTCCAG
59
TTTCCTCAGAAGCCTCTGAG
59
TGATCCAACCGTCCATGAG
60
AGGAGTTTGGAGCAAAGCT
60
CCTGAAGTGAAGAGAACTCCA
60
ACGACTCTGAAAGAGGACAG
59
GATGTTGAAGCTGTGCCTG
60
TTCACTGGTATTGTTACCAGC
58
CCTTCACCACACTTAGCTG
58
TCTTCCAAACATCCCACAC
58
TCATAGTCATCACTTCGGC
57

转录因子

转录因子

转录因子
影响基因
影响类型
参考文献链接（PubMed）
SIRT1
CCAR2
Repression
23892437

基因本体信息

CCAR2基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 质膜
  • 细胞质
  • 细胞外
  • 高尔基体
  • 囊泡
  • 细胞骨架
  • 内质网
  • 细胞核
  • 内体
  • 溶酶体
  • 线粒体

CCAR2基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0006355
A0A087X2B6 (UniProtKB)
IEA
GO:0008380
A0A087X2B6 (UniProtKB)
IEA
GO:0043065
A0A087X2B6 (UniProtKB)
IEA
GO:0044609
A0A087X2B6 (UniProtKB)
IEA
GO:0006355
E5RFJ3 (UniProtKB)
IEA
GO:0008380
E5RFJ3 (UniProtKB)
IEA
GO:0043065
E5RFJ3 (UniProtKB)
IEA
GO:0044609
E5RFJ3 (UniProtKB)
IEA
GO:0006355
E5RGU7 (UniProtKB)
IEA
GO:0008380
E5RGU7 (UniProtKB)
IEA
GO:0043065
E5RGU7 (UniProtKB)
IEA
GO:0044609
E5RGU7 (UniProtKB)
IEA
GO:0006355
E5RHH8 (UniProtKB)
IEA
GO:0008380
E5RHH8 (UniProtKB)
IEA
GO:0043065
E5RHH8 (UniProtKB)
IEA
GO:0044609
E5RHH8 (UniProtKB)
IEA
GO:0006355
E5RHJ4 (UniProtKB)
IEA
GO:0008380
E5RHJ4 (UniProtKB)
IEA
GO:0043065
E5RHJ4 (UniProtKB)
IEA
GO:0044609
E5RHJ4 (UniProtKB)
IEA
GO:0005654
G3V119 (UniProtKB)
IDA
GO:0006355
G3V119 (UniProtKB)
IEA
GO:0008380
G3V119 (UniProtKB)
IEA
GO:0043065
G3V119 (UniProtKB)
IEA
GO:0044609
G3V119 (UniProtKB)
IEA
GO:0006355
H0YB24 (UniProtKB)
IEA
GO:0008380
H0YB24 (UniProtKB)
IEA
GO:0043065
H0YB24 (UniProtKB)
IEA
GO:0044609
H0YB24 (UniProtKB)
IEA
GO:0006355
H0YC58 (UniProtKB)
IEA
GO:0008380
H0YC58 (UniProtKB)
IEA
GO:0043065
H0YC58 (UniProtKB)
IEA
GO:0044609
H0YC58 (UniProtKB)
IEA
GO:0006355
H0YC69 (UniProtKB)
IEA
GO:0008380
H0YC69 (UniProtKB)
IEA
GO:0043065
H0YC69 (UniProtKB)
IEA
GO:0044609
H0YC69 (UniProtKB)
IEA
GO:0000790
Q8N163 (UniProtKB)
IDA
GO:0000993
Q8N163 (UniProtKB)
IDA
GO:0004857
Q8N163 (UniProtKB)
IDA
GO:0004857
Q8N163 (UniProtKB)
IDA
GO:0004857
Q8N163 (UniProtKB)
IMP
GO:0005515
Q8N163 (UniProtKB)
IPI
GO:0005515
Q8N163 (UniProtKB)
IPI
GO:0005515
Q8N163 (UniProtKB)
IPI
GO:0005515
Q8N163 (UniProtKB)
IPI
GO:0005515
Q8N163 (UniProtKB)
IPI
GO:0005515
Q8N163 (UniProtKB)
IPI
GO:0005515
Q8N163 (UniProtKB)
IPI
GO:0005515
Q8N163 (UniProtKB)
IPI
GO:0005515
Q8N163 (UniProtKB)
IPI
GO:0005515
Q8N163 (UniProtKB)
IPI
GO:0005515
Q8N163 (UniProtKB)
IPI
GO:0005515
Q8N163 (UniProtKB)
IPI
GO:0005515
Q8N163 (UniProtKB)
IPI
GO:0005515
Q8N163 (UniProtKB)
IPI
GO:0005515
Q8N163 (UniProtKB)
IPI
GO:0005634
Q8N163 (UniProtKB)
IDA
GO:0005634
Q8N163 (UniProtKB)
IDA
GO:0005634
Q8N163 (UniProtKB)
IDA
GO:0005634
Q8N163 (UniProtKB)
IDA
GO:0005634
Q8N163 (UniProtKB)
IDA
GO:0005634
Q8N163 (UniProtKB)
IDA
GO:0005654
Q8N163 (UniProtKB)
IDA
GO:0005654
Q8N163 (UniProtKB)
TAS
GO:0005654
Q8N163 (UniProtKB)
TAS
GO:0005737
Q8N163 (UniProtKB)
IDA
GO:0005737
Q8N163 (UniProtKB)
IDA
GO:0005737
Q8N163 (UniProtKB)
IDA
GO:0005759
Q8N163 (UniProtKB)
IDA
GO:0006351
Q8N163 (UniProtKB)
IEA
GO:0006397
Q8N163 (UniProtKB)
IEA
GO:0006974
Q8N163 (UniProtKB)
IEA
GO:0007049
Q8N163 (UniProtKB)
IEA
GO:0008380
Q8N163 (UniProtKB)
IMP
GO:0009411
Q8N163 (UniProtKB)
IMP
GO:0016055
Q8N163 (UniProtKB)
IEA
GO:0019899
Q8N163 (UniProtKB)
IPI
GO:0019899
Q8N163 (UniProtKB)
IPI
GO:0019899
Q8N163 (UniProtKB)
IPI
GO:0030308
Q8N163 (UniProtKB)
IMP
GO:0031647
Q8N163 (UniProtKB)
IDA
GO:0032435
Q8N163 (UniProtKB)
IDA
GO:0032784
Q8N163 (UniProtKB)
IMP
GO:0042752
Q8N163 (UniProtKB)
ISS
GO:0043065
Q8N163 (UniProtKB)
IMP
GO:0043065
Q8N163 (UniProtKB)
IMP
GO:0043086
Q8N163 (UniProtKB)
IMP
GO:0043653
Q8N163 (UniProtKB)
IDA
GO:0044609
Q8N163 (UniProtKB)
IDA
GO:0044822
Q8N163 (UniProtKB)
IDA
GO:0044822
Q8N163 (UniProtKB)
IDA
GO:0045892
Q8N163 (UniProtKB)
IMP
GO:0045892
Q8N163 (UniProtKB)
IDA
GO:0045892
Q8N163 (UniProtKB)
IMP
GO:0048511
Q8N163 (UniProtKB)
IEA
GO:0090263
Q8N163 (UniProtKB)
IMP
GO:0090311
Q8N163 (UniProtKB)
IDA
GO:1900034
Q8N163 (UniProtKB)
TAS
GO:1902230
Q8N163 (UniProtKB)
IMP
GO:2000003
Q8N163 (UniProtKB)
IMP
GO:0005681
Q8N163 (UniProtKB)
IDA

基因相关microRNA

基因相关microRNA

可能调控 CCAR2基因的相关microRNA：     

基因相互作用关系

基因相互作用关系

MINT

BioGrid

IntAct

mentha

String

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因通路

基因通路

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Wallerian Degeneration 0.12 1 0 CTD_human
Mammary Neoplasms 0.005720142 3 0 BeFree_LHGDN
Malignant neoplasm of breast 0.001900093 7 0 BeFree
Breast Carcinoma 0.001628651 6 0 BeFree
Carcinogenesis 0.000814326 3 0 BeFree
Stomach Carcinoma 0.000542884 2 0 BeFree
Obesity 0.000542884 2 0 BeFree
Secondary malignant neoplasm of lymph node 0.000542884 2 0 BeFree
Acute lymphocytic leukemia 0.000271442 1 0 BeFree
Carcinoma of bladder 0.000271442 1 0 BeFree

基因相关服务

基因相关服务

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