The protein encoded by this gene shows sequence similarity to the human breast carcinoma metastasis suppressor (BRMS1) protein and the mammalian Sds3 (suppressor of defective silencing 3) proteins. This protein is a component of the mSin3a family of histone deacetylase complexes (HDAC). [provided by RefSeq, Jul 2008]
由该基因编码的蛋白质显示序列相似性的人乳腺癌转移抑制(BRMS1)蛋白质和蛋白质的哺乳动物Sds3(缺陷沉默3的抑制)。这种蛋白质是mSin3a家庭组蛋白脱乙酰复合物(HDAC)的一个组件。 [由RefSeq的,2008年7月提供]
BRMS1L基因(以及对应的蛋白质)的细胞分布位置:
BRMS1L基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Neoplasm Metastasis | 0.015743629 | 58 | 0 | BeFree |
Malignant neoplasm of breast | 0.009771907 | 36 | 0 | BeFree |
Breast Carcinoma | 0.009771907 | 36 | 0 | BeFree |
Thyroid Neoplasm | 0.004734064 | 2 | 2 | GAD |
melanoma | 0.002985861 | 11 | 0 | BeFree |
Chronic Lymphocytic Leukemia | 0.002367032 | 1 | 1 | GAD |
Non-Small Cell Lung Carcinoma | 0.002171535 | 8 | 0 | BeFree |
Tumor Progression | 0.001357209 | 5 | 0 | BeFree |
Mammary Neoplasms | 0.001357209 | 5 | 0 | BeFree |
Ovarian Carcinoma | 0.000814326 | 3 | 0 | BeFree |
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