ANP32D (acidic nuclear phosphoprotein 32 family member D)
- symbol:
- ANP32D
- locus group:
- protein-coding gene
- location:
- 12q13.11
- gene_family:
- ANP32 acidic nuclear phosphoproteins
- alias symbol:
- PP32R2
- alias name:
- pp32 related 2
- entrez id:
- 23519
- ensembl gene id:
- ENSG00000139223
- ucsc gene id:
- uc010slt.3
- refseq accession:
- NM_012404
- hgnc_id:
- HGNC:16676
- approved reserved:
- 2002-02-13
Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is absent in the protein encoded by this gene. This gene does not contain introns. [provided by RefSeq, Jul 2008]
磷蛋白32（PP32对于）是一种肿瘤抑制，可以抑制几种类型的癌症，包括前列腺癌和乳腺癌。由该基因编码的蛋白质是那些在氨基酸序列PP32对于相似，并且相同的酸性核磷蛋白基因家族的一部分的至少两个蛋白之一。然而，与PP32对于，所编码的蛋白质是致瘤的。 PP32对于所述的肿瘤抑制功能已被定位于该是在由该基因编码的蛋白质缺失25个氨基酸的区域。该基因不含内含子。 [由RefSeq的，2008年7月提供]
基因本体信息
ANP32D基因（以及对应的蛋白质）的细胞分布位置：
- 质膜
- 细胞质
- 细胞外
- 高尔基体
- 囊泡
- 细胞骨架
- 内质网
- 细胞核
- 内体
- 溶酶体
- 线粒体
ANP32D基因的本体（GO）信息：
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Chronic mountain sickness | 0.000542884 | 2 | 0 | BeFree |
| Malignant neoplasm of prostate | 0.000271442 | 1 | 0 | BeFree |
| Prostate carcinoma | 0.000271442 | 1 | 0 | BeFree |
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