ACP4 (acid phosphatase 4)
- symbol:
- ACP4
- locus group:
- protein-coding gene
- location:
- 19q13.33
- gene_family:
- alias symbol:
- None
- alias name:
- testicular acid phosphatase
- entrez id:
- 93650
- ensembl gene id:
- ENSG00000142513
- ucsc gene id:
- uc002pta.1
- refseq accession:
- NM_033068
- hgnc_id:
- HGNC:14376
- approved reserved:
- 2001-07-13
Acid phosphatases are enzymes capable of hydrolyzing orthophosphoric acid esters in an acid medium. This gene is up-regulated by androgens and is down-regulated by estrogens in the prostate cancer cell line. This gene exhibits a lower level of expression in testicular cancer tissues than in normal tissues. The protein encoded by this gene has structural similarity to prostatic and lysosomal acid phosphatases. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
酸性磷酸酶能够在酸介质中水解正磷酸酯的酶。该基因是由雄激素上调，通过在前列腺癌细胞系的雌激素是下调。该基因表现出表达的睾丸癌组织一个较低的水平比在正常组织中。由该基因编码的蛋白质具有结构相似性前列腺和溶酶体酸性磷酸酶。可变剪接转录物变体已有描述，但它们的生物有效性尚未确定。 [由RefSeq的，2008年7月提供]
基因本体信息
ACP4基因（以及对应的蛋白质）的细胞分布位置：
- 质膜
- 细胞质
- 细胞外
- 高尔基体
- 囊泡
- 细胞骨架
- 内质网
- 细胞核
- 内体
- 溶酶体
- 线粒体
ACP4基因的本体（GO）信息：
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