GFM2(G elongation factor, mitochondrial 2) 转至新版数据库

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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5q13
基因染色体位置图

Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors, which is a GTPase that plays a role at the termination of mitochondrial translation by mediating the disassembly of ribosomes from messenger RNA . Its role in the regulation of normal mitochondrial function and in disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013]

[中文简述(自动翻译):]  真核生物含有两种蛋白质的平移系统,一个在细胞质中,一个在线粒体中。线粒体翻译是在呼吸链氧化磷酸化系统和受损维护线粒体DNA的维持线粒体功能和突变在本系统中导致击穿至关重要。该基因编码的线粒体翻译延伸因子,它是通过从信使RNA介导的核糖体的拆卸起着在线粒体翻译终止的一个角色的GTP酶之一。其在正常的线粒体功能的调节和归因于线粒体功能障碍的疾病状态的作用是未知的。在多个转录剪接变异体结果不同编码的亚型。 [由RefSeq的,2013年7月提供]

GFM2基因的碱基序列:[NCBI]
GFM2基因的碱基突变:           显示全部snp
rs957680       rs1043968       rs1048088       rs1048167       rs1164691       rs1164693       rs1374694       rs1447452       rs2314936       rs2314937       rs3031208       rs3058458       rs3733793       rs5868753       rs6453075       rs6453076       rs6453077       rs6453078       rs6453079       rs6453081       rs6862623       rs6862630       rs6873912       rs6873998       rs6877188       rs6879781       rs6881010       rs6884338       rs6894177       rs6896033       rs6897850       rs6898684       rs7349790       rs7705519       rs7713812       rs7714615       rs7714771      
rs7732440       rs7732843       rs10057606       rs10075965       rs10462508       rs10515189       rs10515190       rs10515191       rs10515192       rs10515193       rs10515194       rs10942719       rs11556477       rs11741464       rs11743415       rs11743655       rs11746611       rs11948188       rs11950373       rs11951326       rs11952038       rs11954065       rs11956317       rs11960413       rs13159593       rs13164140       rs13165852       rs13184615       rs13190604       rs16872219       rs16872220       rs16872221       rs16872228       rs16872230       rs16872231       rs16872233       rs16872235       rs16872242       rs16872254       rs17647023       rs17670701       rs17738140       rs17738266       rs17852780       rs17852781       rs17856871       rs17856872       rs34172202       rs34220745       rs34654949       rs34833477       rs34845453       rs35080306       rs35313753       rs35491723       rs35512787       rs35541495       rs35565659       rs36116775       rs41271751       rs55870102       rs55996695       rs56127814       rs56365996       rs57549677       rs58054246       rs58864890       rs59110717       rs59475923       rs60077745       rs61093699       rs61373898       rs62366372       rs62366373       rs62366375       rs62366376       rs62366406       rs62366408       rs62366409       rs62366412       rs62635806       rs70976129       rs70976130       rs70976132       rs71600438       rs71627070       rs72764642       rs72764643       rs72764647       rs72764648       rs72764650       rs72764653       rs72764654       rs72764655       rs72764656       rs72764657       rs73114780       rs73114783       rs73114784       rs73114790       rs73114800       rs73762944       rs73762945       rs73762946       rs73762947       rs73762949       rs75359224       rs75543505       rs75750591       rs75898801       rs75974765       rs76108153       rs76339998       rs76560612       rs76566228       rs76839819       rs77099085       rs77231943       rs77437197       rs77478532       rs77555019       rs77892751       rs77925956       rs77987703       rs78086207       rs78325970       rs78674702       rs78859991       rs79205701       rs79357178       rs79449088       rs79550661       rs79558384       rs79669494       rs79814920       rs79992455       rs79992782       rs111257710       rs111275417       rs111382101       rs111472115       rs111538497       rs111561182       rs111570372       rs111573658       rs111631698       rs111760381       rs111819315       rs111826707       rs111979516       rs112000538       rs112150610       rs112155465       rs112221111       rs112355347       rs112525817       rs112531964       rs112611281       rs112613288       rs112686170       rs112725920       rs112796442       rs112800151       rs112808420       rs113233969       rs113290762       rs113347529       rs113418900       rs113558874       rs113773694       rs113865695       rs113923552       rs114172835       rs114282130       rs114533220       rs114542784       rs114568291       rs114606851       rs114825302       rs114852633       rs115032438       rs115208747       rs115239364       rs115273629       rs115566881       rs115655426       rs115932349       rs115983178       rs116058851       rs116165962       rs116523183       rs116582430       rs116606260       rs116658688       rs116684547       rs116770066       rs116830945       rs116857902       rs116980944       rs117914821       rs118133558       rs121907984       rs137940792       rs137985752       rs138008849       rs138107419       rs138108067       rs138225058       rs138328003       rs138388406       rs138467599       rs138649918       rs138670775       rs138677794       rs138756897       rs138769163       rs138873029       rs138941382       rs138942000       rs139000966       rs139021791       rs139120037       rs139165108       rs139191000       rs139234343       rs139270774       rs139377425       rs139397531       rs139515040       rs139811846       rs139901493       rs140072367       rs140077535       rs140248872       rs140421208       rs140535795       rs140543122       rs140600063       rs140627230       rs140747765       rs140790076       rs140855756       rs140968080       rs141000370       rs141024512       rs141077479       rs141161372       rs141187575       rs141187881       rs141252556       rs141320720       rs141358769       rs141364450       rs141452414       rs141460554       rs141660465       rs141762746       rs141789665       rs141800804       rs141831969       rs141864707       rs141886148       rs141938771       rs142050973       rs142164437       rs142185473       rs142201617       rs142425196       rs142427759       rs142840376       rs142845679       rs142926951       rs142986380       rs143041951       rs143133388       rs143199538       rs143232358       rs143233751       rs143306569       rs143351071       rs143396362       rs143460716       rs143461990       rs143465230       rs143635580       rs143880540       rs143986655       rs143994662       rs144202404       rs144416852       rs144523549       rs144582845       rs144641284       rs144747295       rs144835814       rs144900529       rs145136703       rs145221708       rs145235989       rs145277001       rs145433842       rs145473934       rs145597154       rs145610838       rs145654236       rs145665250       rs145724114       rs145802268       rs145820556       rs145914479       rs146227102       rs146259893       rs146350978       rs146631419       rs146647967       rs146656777       rs146690516       rs146763087       rs146779240       rs146794329       rs146811481       rs147129123       rs147231258       rs147252091       rs147355762       rs147446136       rs147606872       rs147905476       rs147917667       rs147925896       rs147934999       rs147935876       rs148220550       rs148239194       rs148508423       rs148582910       rs148621552       rs148709770       rs148749946       rs148779551       rs148976244       rs149012101       rs149101388       rs149150520       rs149163380       rs149204916       rs149216145       rs149256104       rs149505551       rs149532124       rs149540985       rs149576436       rs149721517       rs149737091       rs149772972       rs149774393       rs149978203       rs150034592       rs150085118       rs150138268       rs150250294       rs150271272       rs150278288       rs150296436       rs150298104       rs150344401       rs150438290       rs150544130       rs150612355       rs150654261       rs150747026       rs150828229       rs150876239       rs150919162       rs150953783       rs151093565       rs151111847       rs180789455       rs180792368       rs180796486       rs180801317       rs180820965       rs181065526       rs181294092       rs181307332       rs181312025       rs181330964       rs181523241       rs181669408       rs181693770       rs181718573       rs181737846       rs181749874       rs181888727       rs181900110       rs181909555       rs181913795       rs182112848       rs182115360       rs182174189       rs182175776       rs182311599       rs182324003       rs182440817       rs182444572       rs182698639       rs182715014       rs182728038       rs182739367       rs182930908       rs182942658       rs183016043       rs183016849       rs183165565       rs183167234       rs183175365       rs183285151       rs183365070       rs183372850       rs183381770       rs183548924       rs183570139       rs183665601       rs183887871       rs183890340       rs183916868       rs183976132       rs183985121       rs183986873       rs184071347       rs184203523       rs184208500       rs184213412       rs184278299       rs184287040       rs184422638       rs184465043       rs184488832       rs184609194       rs184670301       rs184732617       rs184858525       rs184888542       rs184903455       rs184908092       rs185031893       rs185134955       rs185155096       rs185292533       rs185548510       rs185655954       rs185671743       rs185892309       rs185906750       rs185908809       rs185958744       rs186033627       rs186049932       rs186168413       rs186213016       rs186221220       rs186299267       rs186435201       rs186461915       rs186551626       rs186718927       rs186795015       rs186851768       rs186858701       rs186931002       rs186932664       rs187037430       rs187164130       rs187166778       rs187175923       rs187328641       rs187367212       rs187556135       rs187572722       rs187576564       rs187630994       rs187799523       rs187803936       rs187809269       rs187910659       rs188062895       rs188066900       rs188162558       rs188303923       rs188306675       rs188319034       rs188422285       rs188452032       rs188559993       rs188566276       rs188946834       rs188960185       rs188965244       rs188968867       rs188970626       rs188990044       rs189466089       rs189615836       rs189622516       rs189680372       rs189691886       rs189698527       rs189729898       rs189736038       rs189754733       rs189943945       rs189998377       rs190112087       rs190236974       rs190269607       rs190373800       rs190379842       rs190510853       rs190530033       rs190533716       rs190608891       rs190627495       rs190772207       rs190778103       rs191001559       rs191007875       rs191033237       rs191038496       rs191273466       rs191279844       rs191287159       rs191303127       rs191503023       rs191509054       rs191531421       rs191580162       rs191767372       rs191778555       rs191829393       rs192026955       rs192028855       rs192038195       rs192144054       rs192274004       rs192366505       rs192382717       rs192389282       rs192405928       rs192520119       rs192581658       rs192581724       rs192675776       rs192687922       rs192738187       rs192815461       rs192818221       rs192887099       rs192946899       rs193007628       rs193085498       rs193126417       rs193207594       rs199681606       rs199781577       rs199839942       rs199843112       rs199920365       rs200151202       rs200196786       rs200232238       rs200354135       rs200473701       rs200526753       rs200652138       rs200892870       rs200897090       rs201009516       rs201042618       rs201136632       rs201174367       rs201204413       rs201213722       rs201448394       rs201580206       rs201783554       rs201950341       rs202067734       rs202077801       rs202101111       rs202156972       rs367655807       rs367671559       rs367672600       rs367676220       rs367889795       rs367960522       rs367972290       rs368007197       rs368096438       rs368261628       rs368688699       rs368755569       rs368796956       rs368894755       rs369071633       rs369168318       rs369293025       rs369299315       rs369332450       rs369517500       rs369709831       rs369800782       rs369964880       rs369990115       rs370262957       rs370322397       rs370351589       rs370359140       rs370638683       rs370662106       rs370711342       rs370838336       rs370943169       rs371028042       rs371028297       rs371096174       rs371555085       rs371589931       rs371717663       rs371762138       rs372005240       rs372145413       rs372461509       rs372536068       rs372562849       rs372593186       rs372687626       rs372720848       rs372830570       rs373327256       rs373374362       rs373499834       rs373586427       rs373744247       rs373760911       rs373899907       rs374064184       rs374129117       rs374139134       rs374151998       rs374162426       rs374177328       rs374426323       rs374614628       rs374698121       rs374809642       rs374912826       rs374950698       rs375010693       rs375032994       rs375152899       rs375258233       rs375335360       rs375349328       rs375372058       rs375461081       rs375616454       rs375710933       rs375767089       rs375791445       rs375912721       rs375996126       rs376249756       rs376307302       rs376372312       rs376500994       rs376643899       rs377159763       rs377216980       rs377321462       rs377349830       rs377355527       rs377463681       rs377512993       rs377533296       rs377591652       rs377655338       rs397998155       rs397998156       rs398123448       rs527377580       rs527440565       rs527501112       rs527564162       rs527628618       rs527685277       rs527691009       rs527750819       rs527811974       rs527847775       rs527912879       rs527912893       rs528098366       rs528305784       rs528367490       rs528437291       rs528511715       rs528516871       rs528572203       rs528642095       rs528767218       rs528813726       rs528969479       rs528982897       rs529051980       rs529166518       rs529182105       rs529182251       rs529214882       rs529342181       rs529386669       rs529451525       rs529589563       rs529752365       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rs761709918       rs761782791       rs761809459       rs761862224       rs761908335       rs762158006       rs762159332       rs762181767       rs762256283       rs762257781       rs762444418       rs762453862       rs762523757       rs762538154       rs762565992       rs762579866       rs762644818       rs762657718       rs762658553       rs762693230       rs762748293       rs762836355       rs762900464       rs762931936       rs763012299       rs763038574       rs763177573       rs763337433       rs763385749       rs763412114       rs763475083       rs763572134       rs763621033       rs763774517       rs763845730       rs763894178       rs763927371       rs763933998       rs763999996       rs764105920       rs764127754       rs764298909       rs764388268       rs764493098       rs764498961       rs764552042       rs764685887       rs764863051       rs764931275       rs764950060       rs764956337       rs765042058       rs765078389       rs765124597       rs765145293       rs765235690       rs765325575       rs765432280       rs765471025       rs765649591       rs765702596       rs765737516       rs765808461       rs765847834       rs765865557       rs765870953       rs765964533       rs765999515       rs766053718       rs766229932       rs766242615       rs766244410       rs766428077       rs766477016       rs766526804       rs766593015       rs766593352       rs766617868       rs766635463       rs766706040       rs766791577       rs766819046       rs766931652       rs766952588       rs766962387       rs767104849       rs767191130       rs767192636       rs767328479       rs767434976       rs767442986       rs767547716       rs767564629       rs767624997       rs767663018       rs767689482       rs767704309       rs767729351       rs767915983       rs767924691       rs768012567       rs768051849       rs768185080       rs768241825       rs768265245       rs768369351       rs768396838       rs768562682       rs768565469       rs768622368       rs768637054       rs768728438       rs768742394       rs768900309       rs768983066       rs769010962       rs769012312       rs769035648       rs769129792       rs769170930       rs769208361       rs769283153       rs769345129       rs769378661       rs769415925       rs769507719       rs769555721       rs769555873       rs769692043       rs769700489       rs769752382       rs769767706       rs769792893       rs769887272       rs770039644       rs770121989       rs770126807       rs770151099       rs770232570       rs770257461       rs770290784       rs770320378       rs770347396       rs770418085       rs770447666       rs770485054       rs770560389       rs770582944       rs770699057       rs770719415       rs770752206       rs770823586       rs770890779       rs770910279       rs770911457       rs770950512       rs770958798       rs771040120       rs771141000       rs771161706       rs771215231       rs771248497       rs771338321       rs771360110       rs771414578       rs771437314       rs771506320       rs771592465       rs771614645       rs771656661       rs771790901       rs771890541       rs771908502       rs771941037       rs771986836       rs772030907       rs772073181       rs772132644       rs772191122       rs772220948       rs772321151       rs772410310       rs772416581       rs772432450       rs772506292       rs772578794       rs772685304       rs772690808       rs772764501       rs772778721       rs772951064       rs773006254       rs773010798       rs773011043       rs773063877       rs773129897       rs773135306       rs773272075       rs773310266       rs773370155       rs773375495       rs773397551       rs773425115       rs773571926       rs773615422       rs773642837       rs773778306       rs773797714       rs773824800       rs773947727       rs773995570       rs774084578       rs774162984       rs774182712       rs774271112       rs774282023       rs774367605       rs774464063       rs774469633       rs774479755       rs774544255       rs774652872       rs774740228       rs774771409       rs774850402       rs774851843       rs774926981       rs774940465       rs774966146       rs775015994       rs775214088       rs775222955       rs775321450       rs775323042       rs775336704       rs775493482       rs775507625       rs775517339       rs775595121       rs775606940       rs775618593       rs775679100       rs775689852       rs775709265       rs775748234       rs775884451       rs775975776       rs775994813       rs776061962       rs776170203       rs776182710       rs776188344       rs776338602       rs776357804       rs776369168       rs776379556       rs776533541       rs776564805       rs776623723       rs776661978       rs776671031       rs776692804       rs776748857       rs776751350       rs776757077       rs776814499       rs776817056       rs776855166       rs777007726       rs777009900       rs777105528       rs777129105       rs777198322       rs777391712       rs777584659       rs777703250       rs777744066       rs777960136       rs777978991       rs778040866       rs778047131       rs778068938       rs778082283       rs778101294       rs778131750       rs778134382       rs778170012       rs778276331       rs778357315       rs778385185       rs778413098       rs778446572       rs778603093       rs778605094       rs778636828       rs778742375       rs778846963       rs778863487       rs778979352       rs779107967       rs779181943       rs779204902       rs779214119       rs779215814       rs779299760       rs779300161       rs779302200       rs779406631       rs779481314       rs779505164       rs779515606       rs779582321       rs779666774       rs779682616       rs779755199       rs779954004       rs780029934       rs780042669       rs780052555       rs780130081       rs780138908       rs780360214       rs780442536       rs780443117       rs780502340       rs780565241       rs780628654       rs780691008       rs780831312       rs780917501       rs781014488       rs781015127       rs781105678       rs781202718       rs781307835       rs781383140       rs781432653       rs781474781       rs781474974       rs781488424       rs781492524       rs781672459       rs781675849       rs540663056       rs116770066      

GFM2基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
ATCACTGGGAGGTCATGTG
59
ATCAAATACAGCCACTGCAC
59
ATCACTGGGAGGTCATGTG
59
CATCAAATACAGCCACTGCA
59
GTGGAGATTCCAGAACCTG
57
CAACGCATGTTCCAAATCTG
58
GAGTGGAGATTCCAGAACCT
58
ACGCATGTTCCAAATCTGG
58
TAATGGAAACTGCACGGAG
58
TACCAGCAGTCAATGAAGG
57
GAGCGTAACTATGAATTTCTGGAG
60
CCAGCAGTCAATGAAGGGA
60
CATGCGTTGAAATGTCTTCAG
59
CTATCTAAGGTATTTGTCCAGAGTC
59
TAATGGAAACTGCACGGAG
58
TACCAGCAGTCAATGAAGG
57
GAATGGCCAGACTGTTCTG
59
TCTCCAGTCCATATTCCCTC
58
GATGATGAATTTGCTGACTTGG
58
CTATGTATTGCAGTCTGTAGCT
57
      尚未收录相关数据

GFM2基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

GFM2基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0003924
D6RAL1(UniProtKB)
IEA
GO:0005525
D6RAL1(UniProtKB)
IEA
GO:0003924
D6RF75(UniProtKB)
IEA
GO:0005525
D6RF75(UniProtKB)
IEA
GO:0003924
Q969S9(UniProtKB)
EXP
GO:0003924
Q969S9(UniProtKB)
IDA
GO:0005515
Q969S9(UniProtKB)
IPI
GO:0005515
Q969S9(UniProtKB)
IPI
GO:0005515
Q969S9(UniProtKB)
IPI
GO:0005515
Q969S9(UniProtKB)
IPI
GO:0005525
Q969S9(UniProtKB)
IEA
GO:0005622
Q969S9(UniProtKB)
IBA
GO:0005759
Q969S9(UniProtKB)
TAS
GO:0005759
Q969S9(UniProtKB)
TAS
GO:0032543
Q969S9(UniProtKB)
IDA
GO:0032790
Q969S9(UniProtKB)
IDA
GO:0070126
Q969S9(UniProtKB)
TAS
GO:0003746
Q969S9(UniProtKB)
IDA
GO:0070125
Q969S9(UniProtKB)
IDA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控GFM2基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
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