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Translation control during prolonged mTORC1 inhibition mediated by 4E-BP3.

Tsukumo(Yoshinori),Alain(Tommy),Fonseca(Br... Nat Commun 0000-00-00

...CRISPR/Cas9-mediated EIF4EBP3 gene disruption in human cancer cells mitigated the inhibition of translation and prolifer...

Unhealthy Sugars in Bacterial Cytotoxicity.

Aguilar-Salvador(D Isui),Tran Van Nhieu(Gu... Cell Host Microbe 0000-00-00

...CRISPR/Cas technology to identify a role for cell surface sulfation and fucosylation in cytotoxicity mediated by Vibrio ...

The Dual NOD1/NOD2 Agonism of Muropeptides Containing a Meso-Diaminopimelic A...

Dagil(Yulia A),Arbatsky(Nikolai P),Alkhazo... PLoS One 0000-00-00

...CRISPR/Cas9-mediated knockout (KO) of NOD1 and NOD2 genes in modified HEK293T cells. Using NOD1/NOD2 knockout and overex...

Genomic Amplifications Cause False Positives in CRISPR Screens.

Sheel(Ankur),Xue(Wen) Cancer Discov 0000-00-00

In CRISPR-based screens for essential genes, Munoz and colleagues and Aguirre and colleagues show that gene-independent ...

Human ULK1 Variation and Susceptibility to Mycobacterium tuberculosis Infection.

Horne(David J),Graustein(Andrew D),Shah(Ja... J Infect Dis 0000-00-00

...CRISPR/Cas9 in U937 monocytes, we investigated the effect of ULK1 deficiency on cytokine expression, autophagy, and M. t...

Successful in vitro fertilization and generation of transgenics in Black and ...

Baan(Mieke),Krentz(Kathleen J),Fontaine(Da... Transgenic Res 0000-00-00

...CRISPR/Cas9. These methods also allow effective colony preservation and rederivation with these strains. To our knowledg...

Application of NanoLuc to monitor the intrinsic promoter activity of GRP78 us...

Oh-Hashi(Kentaro),Furuta(Eri),Norisada(Jun... Genes Cells 0000-00-00

In this study, we applied a highly sensitive small luciferase, NanoLuc, to establish a knock-in cell line using the CRIS...

High-efficiency CRISPR/Cas9 multiplex gene editing using the glycine tRNA-pro...

Qi(Weiwei),Zhu(Tong),Tian(Zhongrui),Li(Cha... BMC Biotechnol 0000-00-00

CRISPR/Cas9 genome editing strategy has been applied to a variety of species and the tRNA-processing system has been use...

CRISPR-Cas9 gene editing: Delivery aspects and therapeutic potential.

Oude Blenke(Erik),Evers(Martijn J W),Mastr... J Control Release 0000-00-00

...CRISPR), together with CRISPR-associated proteins (Cas) are a part of the prokaryotic adaptive immune system and have su...

Inhibition of histone deacetylase reduces transcription of NADPH oxidases and...

Chen(Feng),Li(Xueyi),Aquadro(Emily),Haigh(... Free Radic Biol Med 0000-00-00

...CRISPR-ON to drive transcription of Nox1, Nox2, Nox4 and Nox5 genes is blocked by HDAC inhibitors. In a monocrotaline (M...

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