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EIF2S1-PELO co-expression architecture in human brain: pairing-family decompo...

Harbert(DH) Front Mol Neurosci None

...CRISPR screens is essentially zero (Jaccard = 0.006, gene-effect Pearson r = -0.07), consistent with layer separation be...

SLC3A2 promotes early-stage of Zika virus infection in human placental cells ...

Chen(Z),Feng(D),Liu(J),Chen(J),Zhao(C),Zha... Infect Dis Immun 2026-07-00

...CRISPR-Cas9 and classical virological experiments were performed to identify SLC3A2 functions in ZIKV entry and infectio...

Variant-to-function mapping in lupus links IL12A to the expansion of disease-...

Colantuoni(M),Xiao(Q),Aziz(NA),Aguiar(VRC)... medRxiv 2026-07-29

...CRISPR-based tools in a B cell line, we validated this region as an enhancer, rs485499 as a likely causal variant and es...

The role of HIL1 in strain-level adhesion and immune recognition in Debaryomy...

Newhall(KP),de Sousa Bezerra(AV),Goddard(J... mBio 2026-07-30

...CRISPR-Cas9-mediated deletion of HIL1 recapitulated the mutant phenotype, demonstrating that HIL1 was necessary for biof...

Role of HIF-1α-SERPINE1 axis in hypoxia-induced trophoblast invasion and its ...

Zhang(Y),Dong(H),Wang(S),Zhang(F),Zhang(B) Tissue Cell 2026-07-27

...CRISPR/Cas9-generated SERPINE1 knockout (KO) mouse model was used to assess pregnancy outcomes with WT controls included...

Enhanced replication and immunogenicity of a genome-modified non-replicating ...

Ren(J),Liu(S),Yuan(H),Wu(Y),Zhao(Z),Wang(Y... J Virol 2026-08-18

...CRISPR/Cas9-mediated gene editing and homologous recombination. The resulting construct, designated NTV-ΔF1L-C7L, exhibi...

Development and clinical validation of a CRISPR/Cas9-engineered reporter phag...

Hao(Z),Zhao(Q),Zhong(Y),Li(M),Wang(C),Wang(C) Microbiol Spectr 2026-08-06

...CRISPR/Cas9 system combined with homologous recombination. One-step growth curves, optimal multiplicity of infection, an...

PRMT7-mediated arginine methylation of FOXK activates Wnt/β-catenin signallin...

Zhao(X),Zhang(J),Teng(Y),Wang(Y),Yu(W),Sun... Clin Transl Med 2026-09-00

...CRISPR/Cas9‑mediated knockout and overexpression systems, combined with in vitro assays for proliferation, apoptosis and...

Glutathione reductase deficiency potentiates the immunogenicity of ferroptosi...

Deng(X),Deng(Z),Zhu(B),Hu(R),Ma(J),Li(C),Z... J Hematol Oncol 2026-09-01

...CRISPR knockout screen was performed to identify key regulators of ferroptosis. Genetic depletion or pharmacological inh...

Integrated multi-omics analysis and functional experiments reveals PPAP2C as ...

Lin(X),Cen(L),Yue(S),Teng(L),Qin(S),Cheng(... Front Pharmacol 2026-00-00

...CRISPR-Cas9-mediated knockout and ectopic overexpression, with assessment of key phenotypes including proliferation, col...

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