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TP53 BRCA1 CRISPR single-cell cancer

Lai(H),Hu(G),Cui(Y),Yu(X) Appl Environ Microbiol 2026-08-19

...CRISPR-Cas9 technology, we constructed a sho1 gene knockout mutant to examine its phenotypic and molecular responses to ...

Zhu(Q),Feng(S),Yan(Z),Wang(Z),Huang(X),Sun... Front Immunol None

...CRISPR-Cas9-mediated chromosomal integration strategies were compared. Structural modeling and molecular dynamics simula...

Zhang(X),Habib(A),McFarlin(S),Richart(D),P... bioRxiv 2026-06-03

...CRISPR-mediated knockout of TBC1D23 severely impairs rAAV transduction across multiple human cell types, including polar...

Yu(Y-C),Tumen-Velasquez(M),Vergara(MM),Ale... Appl Environ Microbiol 2026-07-22

...CRISPR interference library for functional genomic screening. Collectively, our results identify an RM system that has, ...

Zhou(Y),Geng(H),Xu(Y),Hong(Y),Mei(B),Wu(H)... J Exp Clin Cancer Res 2026-06-27

...CRISPR/Cas9-mediated Ifnar1 knockdown. Finally, the synergistic efficacy of anti-PD-1 combined with MEK inhibition (Tram...

Li(T),Huang(S),Zhang(J),Liu(X),Zhu(L),Li(Y... Front Immunol None

...CRISPR knockout of GSDMD, but not of Bax, prevented this injury-induced mitochondrial dysfunction. Delayed pharmacologic...

Cudjoe(E),Thorsen(M),Molokwu(N),Russo(M) Clin Ther 2026-07-00

...CRISPR-Cas9 and base-editing technologies. Lipid nanoparticle (LNP) and viral vector delivery platforms enabled efficien...

Su(YL),Huang(SY),Kuo(CW),Xiao(LY),Lin(CT),... J Immunother Cancer 2026-07-07

...CRISPR/Cas9-mediated knockout syngeneic murine models treated with anti-PD-L1 to assess tumor growth, immune infiltratio...

Chen(QQ),Lei(L),Qiu(X),Liu(YJ),Liu(P),Li(R... J Assist Reprod Genet 2026-07-00

...CRISPR/Cas9 (targeting exons 1-3). Testicular histology (hematoxylin-eosin [H&E] staining), sperm parameters (morphology...

Hu(J),Zhang(J),Shao(Y),Li(H),Yang(Y),Zhang(J) Hum Gene Ther 2026-09-00

...CRISPR/Cas9 gene-editing technology. In this study, we conjugated Cbl-b sgRNA with Cas9 protein to form ribonucleoprotei...

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