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MCPIP1 Endoribonuclease Activity Negatively Regulates Interleukin-17-Mediated S…

Garg(Abhishek V),Amatya(Nilesh),Chen(Kong),C… Immunity 2016-01-04

...Nfkbiz, encoding the IκBζ transcription factor. Unexpectedly, MCPIP1 degraded Il17ra and Il17rc mRNA, independently of t...

Molecular-biological analysis of the effect of methamphetamine on the heart in …

Shinone(K),Tomita(M),Inoue(H),Nakagawa(Y),Ik… Leg Med (Tokyo) 2010-03-00

...Nfkbiz, Nr4a1 and Dusp1 changed significantly after the administration of MAP, suggesting the induction of an inflammato...

IL-17-driven transcriptional programs in muscle fibroblasts are not required fo…

Li(D),Reay(DP),Li(Y),Vyas(SP),Yamamoto(K),As… J Immunol 2026-08-04

...Nfkbiz, which encodes IκBζ, a noncanonical NF-κB transcriptional coactivator known to be key for pathologic IL-17 signal...

IκBζ Regulates Human Monocyte Pro-Inflammatory Responses Induced by Streptococc…

Sundaram(Kruthika),Rahman(Mohd Akhlakur),Mit… PLoS One 0000-00-00

...NFKBIZ gene, encoding the transcription factor IκBζ, are associated with increased susceptibility to invasive pneumococc...

Somatic inflammatory gene mutations in human ulcerative colitis epithelium.

Nanki(K),Fujii(M),Shimokawa(M),Matano(M),Nis… Nature 2020-00-00

...NFKBIZ, ZC3H12A and PIGR, which are genes that are rarely affected in colon cancer. Targeted sequencing validates the pe...

Toll-like receptor 9 signaling in chronic lymphocytic leukemia cell lines.

Meloni(M),Sana(I),Mantione(ME),Riba(M),Muzio… FEBS Open Bio 2023-00-00

...NFKBIZ mRNA and the corresponding IkBz protein as robust markers of TLR9 activation in both MEC2 and PCL12, but not in H...

Targetable genetic features of primary testicular and primary central nervous s…

Chapuy(Bjoern),Roemer(Margaretha G M),Stewar… Blood 2016-07-01

...NFKBIZ amplification, frequent concurrent B-cell receptor pathway activation, and deregulation of BCL6. Of great interes...

SARS-CoV-2 RNA stabilizes host mRNAs to elicit immunopathogenesis.

Zhao(H),Cai(Z),Rao(J),Wu(D),Ji(L),Ye(R),Wang… Mol Cell 2024-02-01

...NFKBIZ was crucial for promoting cytokine production and reducing interferon responses, probably contributing to cytokin...

Toll-like receptor 9 stimulation can induce IκBζ expression and IgM secretion i…

Fonte(E),Vilia(MG),Reverberi(D),Sana(I),Scar… Haematologica 2017-00-00

...NFKBIZ mRNA in all the samples analyzed, it induces the IκBζ protein in a selected group of cases, through an unanticipa...

IL-17 integrates multiple self-reinforcing, feed-forward mechanisms through the…

Amatya(N),Childs(EE),Cruz(JA),Aggor(FEY),Gar… Sci Signal 2018-00-09

...Nfkbiz ) and C/EBPβ (Cebpb). These TFs in turn transactivated IL-17-dependent promoters. Together, these data indicated ...

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