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Makarova(Kira S),Koonin(Eugene V) Methods Mol Biol 2016-02-08

...CRISPR)-Cas (CRISPR-associated proteins) is a prokaryotic adaptive immune system that is represented in most archaea and...

Yang(Siyu),Liu(Jing),Shao(Fuye),Wang(Pengf... Biochem Biophys Res Commun 2015-11-10

...CRISPR loci and the CRISPR associated gene (Cas) in 32 S. aureus strains from CRISPR database. Five spacers of S. aureus...

Heussler(Gary E),Cady(Kyle C),Koeppen(Katj... MBio 2016-01-11

...CRISPR)/CRISPR-associated (CRISPR/Cas) system is an adaptive immune system present in many archaea and bacteria. CRISPR/...

Oh(Jee-Hwan),van Pijkeren(Jan-Peter) Nucleic Acids Res 2015-02-26

...CRISPRs) and the CRISPR-associated (Cas) nuclease protect bacteria and archeae from foreign DNA by site-specific cleavag...

Yoder(Kristine E),Bundschuh(Ralf) Sci Rep 0000-00-00

CRISPR/Cas9 genome editing has been proposed as a therapeutic treatment for HIV-1 infection. CRISPR/Cas9 induced double ...

Richter(Hagen),Zoephel(Judith),Schermuly(J... Nucleic Acids Res 2013-01-14

...CRISPR) RNAs (crRNAs). These RNA molecules can contain fragments of viral genomes and mediate, together with a set of CR...

Lummerstorfer(M),Lächelt(U) Drug Deliv 2026-12-31

...CRISPR applications. Given the permanent nature of genome editing, prolonged expression of the CRISPR machinery is not r...

Gophna(Uri),Brodt(Avital) Mob Genet Elements 0000-00-00

...CRISPR arrays are transcribed and processed into small CRISPR RNA molecules, which base-pair with invading DNA or RNA an...

Kiro(Ruth),Shitrit(Dror),Qimron(Udi) RNA Biol 2014-10-29

...CRISPR)-CRISPR-associated (Cas) system has recently been used to engineer genomes of various organisms, but surprisingly...

Mohanraju(Prarthana),Makarova(Kira S),Zets... Science 2016-09-22

...CRISPR-Cas research that reveal elaborate molecular mechanisms and provide for a plausible scenario of CRISPR-Cas evolut...