...SRSF1 is regulated by multisite phosphorylation of a long Arg-Ser repeat in the N-terminus of the RS domain while subnuc...
...SRSF1). Data were generated using two different microarray platforms. The PCR-based validation rate of the top 20 ranked...
...SRSF1 or ASF/SF2) and SRSF2 (SC35). NSrp70 mediates alternative splice site selection, targeting several pre-mRNAs, incl...
...SRSF1 and SRSF9 promote β-catenin accumulation via the recruitment of β-catenin mRNA and by enhancing its translation in...
...SRSF1/SF2 from nuclear speckles in HeLa cells. Treatment with tubercidin also decreased steady-state MALAT1 long ncRNA, ...
...SRSF1 pseudo-RRM bound to RNA, we discovered a very unusual and sequence-specific RNA-binding mode that is centered on o...
...SRSF1, we showed that several residues in the RNA-binding motif 2 interact with the N-terminal region of the RS domain (...
...SRSF1) and pre-mRNAs. Mechanistically, MALAT1 promotes the condensation of SRSF1, and the condensates are preferentially...
...SRSF1 and SRSF2 are overexpressed in 63% and 65% of lung adenocarcinoma (ADC) as well as in 68% and 91% of squamous cell...
...SRSF1)], a prototype for the SR protein family, is regiospecifically phosphorylated by SRPK1, a post-translational modif...
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