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Pharmacological modulation of LMNA SRSF1-dependent splicing abrogates diet-in...

Santo(J),Lopez-Herrera(C),Apolit(C),Barech... Int J Obes (Lond) 0000-00-00

...SRSF1 that contribute to the production of these different isoforms as a target to uncover new anti-obesity drug.,Small ...

Predicting sequence and structural specificities of RNA binding regions recog...

Wang(Xin),Juan(Liran),Lv(Junjie),Wang(Keju... BMC Genomics 2012-06-18

...SRSF1, PTBP1, NOVA and fox2 proteins. These studies either adopted traditional methods like Multiple EM for Motif Elicit...

The SRSF1 linker induces semi-conservative ESE binding by cooperating with th...

Cho(Suhyung),Hoang(Amy),Chakrabarti(Sutapa... Nucleic Acids Res 2012-01-30

...SRSF1 optimally binds to decameric purine rich ESE sequences although locations of purines are not stringently specified...

Primary structural features of SR-like protein acinusS govern the phosphoryla...

Liang(Ning),Zeng(Chuyue),Tao(Kin Pong),Sou... Biochem J 2014-05-05

...SRSF1 (serine/arginine splicing factor 1) at multiple sites using a directional and processive mechanism. Such ability t...

Reduced SRSF1 Expression Correlates with LCK Exon Skipping and Impaired Treg ...

Hu(X),Leng(S),Liu(Y),Zhao(R),Liu(X),Li(J),... Blood 2026-08-17

...SRSF1 as a direct upstream regulator of LCK exon 8 skipping. Notably, SRSF1 expression was reduced in CD4+ naive T cells...

The Splicing Factor SRSF1 as a Marker for Endothelial Senescence.

Blanco(Francisco Javier),Bernabéu(Carmelo) Front Physiol 2012-10-02

...SRSF1, or ASF/SF2) during endothelial senescence, a process that is associated with a differential subcellular localizat...

HnRNP A1 controls a splicing regulatory circuit promoting mesenchymal-to-epit...

Bonomi(Serena),di Matteo(Anna),Buratti(Ema... Nucleic Acids Res 2013-12-03

...SRSF1 directly binds to the enhancer, induces the production of ΔRon and activates EMT leading to cell locomotion. Inter...

Characterization of RNA-Protein Interactions: Lessons from Two RNA-Binding Pr...

Skrdlant(Lindsey),Lin(Ren-Jang) Methods Mol Biol 0000-00-00

...SRSF1 and SRSF2 are two of the most highly studied RNA-binding proteins. Here we examine the various methods used to dif...

Loss of Pnn expression results in mouse early embryonic lethality and cellula...

Leu(Steve),Lin(Yen-Ming),Wu(Chu-Han),Ouyan... J Cell Sci 2013-01-17

...SRSF1 as well as of apoptosis-related genes Bcl-x and ICAD were altered, and expression levels of Bim isoforms were modu...

Tissue-specific and SRSF1-dependent splicing of fibronectin, a matrix protein...

Lopez-Mejia(Isabel Cristina),De Toledo(Mar... Mol Biol Cell 2014-05-06

...SRSF1 protein levels. In the broader context of cancer pathology, the results suggest that SRSF1 might play a central ro...

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