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Dealing with the evolutionary downside of CRISPR immunity: bacteria and benefic…

Jiang(Wenyan),Maniv(Inbal),Arain(Fawaz),Wang… PLoS Genet 2014-03-21

...CRISPR-Cas immunity and its implications for the maintenance of CRISPR-Cas loci in microbial populations. We analyzed th...

Diversity, activity, and evolution of CRISPR loci in Streptococcus thermophilus.

Horvath(Philippe),Romero(Dennis A),Coûté-Mon… J Bacteriol 2008-07-02

...CRISPR activity and propose that the activity is highest for CRISPR1, followed by CRISPR3, while CRISPR2 may be degenera...

CRISPR technologies for bacterial systems: Current achievements and future dire…

Choi(Kyeong Rok),Lee(Sang Yup) Biotechnol Adv 0000-00-00

...CRISPR/Cas systems and the milestone inventions that enabled numerous CRISPR technologies. Next, we describe CRISPR/Cas-...

CRISPRTarget: bioinformatic prediction and analysis of crRNA targets.

Biswas(Ambarish),Gagnon(Joshua N),Brouns(Sta… RNA Biol 2014-01-28

...CRISPR. We use this information to provide a tool (CRISPRTarget) that predicts the most likely targets of CRISPR RNAs (h...

nf-core/crisprseq: a versatile pipeline for comprehensive analysis of CRISPR ge…

Mir-Pedrol(J),Kuhlburger(L),Sanvicente-Garcí… NAR Genom Bioinform 2026-03-00

...CRISPR activation (CRISPRa), CRISPR interference (CRISPRi), CRISPR screens, base editing, and prime editing. The share o...

Delivering a multi-color, cell-based CRISPR experience to low-resource classroo…

Walters(AJ),Lyons(AT),Williams(AA),Porter(D)… J Microbiol Biol Educ 2026-04-30

...CRISPR educational tools, providing hands-on access to CRISPR-based experiences for previously unserved and underserved ...

The solution structure of an anti-CRISPR protein.

Maxwell(Karen L),Garcia(Bianca),Bondy-Denomy… Nat Commun 0000-00-00

...CRISPR proteins that inactivate the type I-F and I-E CRISPR-Cas systems using distinct mechanisms. Here, we present the ...

Polymorphism of CRISPR shows separated natural groupings of Shigella subtypes a…

Yang(Chaojie),Li(Peng),Su(Wenli),Li(Hao),Liu… RNA Biol 2016-05-17

...CRISPR locus. We amplified and analyzed 6 CRISPR loci from 237 Shigella strains belonging to the 4 species groups, as we...

CRISPR decoys: competitive inhibitors of CRISPR immunity.

Maniv(Inbal),Hatoum-Aslan(Asma),Marraffini(L… RNA Biol 2014-01-28

...CRISPR decoys, plasmids containing a non-transcribed repeat-spacer unit that disrupt CRISPR immunity. We show that decoy...

Archaeal CRISPR-based immune systems: exchangeable functional modules.

Garrett(Roger A),Vestergaard(Gisle),Shah(Shi… Trends Microbiol 2012-02-07

...CRISPR transcripts to yield mature CRISPR RNAs (crRNAs), and the targeting and cleavage of foreign nucleic acid. The pri...

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