...TP53 mutations, whereas SMAD4 loss promotes tumor progression. Multi-omics profiling reveals epigenetic repression of th...
...TP53 mutation (TP53 Mut) and p53 abnormal expression (p53Abn), correlates with TAM phenotypic and functional heterogenei...
...TP53 aberration, patients demonstrating mutated IGHV (median PFS time: not reached vs 59.3 months, P= 0.019) and the abs...
...TP53 pathway abnormalities, and are correlated with chemoresistance and poor prognosis. This review summarizes the struc...
...TP53 dysfunction, mechanistic target of rapamycin complex 1 (mTORC1) signaling activation, and pro-inflammatory response...
...TP53, DAXX, DNMT3A, and KMT2A somatic mutations, and TOP2A overexpression), despite stable microsatellite status. Guided...
Patients with myelodysplastic syndrome (MDS)/acute myeloid leukemia (AML) with high-risk features including TP53 mutatio...
...TP53 inactivation according to the new WHO classification in an HIV patient in a well-controlled environment. A bone mar...
...TP53 mutations, suggesting maladaptive somatic rescue. Our findings establish MDM4 deficiency as a TP53-activating syndr...
...TP53-only versus TP53 + EGFR = 13.4 (10.1-16.9); EGFR-only versus TP53 + EGFR = 7.7 (5.3-11.6); TP53-only versus TP53 + ...
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