Fregoso(Oliver I),Das(Shipra),Akerman(Mart... Mol Cell 2013-06-10

...SRSF1, which is overexpressed in many cancers, stabilizes the tumor suppressor protein p53 by abrogating its MDM2-depend...

Comiskey(Daniel F),Jacob(Aishwarya G),Sing... Nucleic Acids Res 2015-07-21

...SRSF1 binds exon 11 at evolutionarily conserved sites. Interestingly, mutations disrupting this interaction proved suffi...

Shultz(Jacqueline C),Goehe(Rachel W),Murud... Mol Cancer Res 2011-11-14

...SRSF1 specifically interacted with this sequence, which was required for SRSF1 to act as a splicing enhancer of the incl...

Pradeepa(Madapura M),Sutherland(Heidi G),U... PLoS Genet 2012-09-26

...Srsf1 and other proteins involved in mRNA processing. The level of H3K36me3 associated Srsf1 is reduced in Psip1 mutant ...

Thorsen(Kasper),Mansilla(Francisco),Schepe... Mol Cell Proteomics 2011-04-06

...SRSF1 to bind predominantly to the cancer associated exon 4B, hence, it was hypothesized that SRPK1 activates SRSF1 thro...

Leva(Valentina),Giuliano(Serena),Bardoni(A... Nucleic Acids Res 2012-04-02

...SRSF1 is hyperphosphorylated in 46BR.1G1 cells compared to control fibroblasts. This hyperphosphorylation can be partial...

Akaike(Yoko),Kurokawa(Ken),Kajita(Keisuke)... J Med Invest 2012-01-23

...srsf1 gene encodes serine/arginine-rich splicing factor 1 (SRSF1) that participates in both constitutive and alternative...

Best(Andrew),Dagliesh(Caroline),Ehrmann(In... Int J Cell Biol 2013-08-12

...SRSF1 gene expression. Increased concentrations of SRSF1 protein promote prooncogenic splicing patterns of a number of k...

Gautrey(Hannah L),Tyson-Capper(Alison J) PLoS One 2013-06-17

...SRSF1 is involved in other aspects of Mcl-1 regulation with knockdown of SRSF1, by RNAi, resulting in a significant decr...

Cho(Suhyung),Hoang(Amy),Sinha(Rahul),Zhong... Proc Natl Acad Sci U S A 2011-07-26

...SRSF1), which bridges the RRM of U1-70K to pre-mRNA by using the surface opposite to the RNA binding site. Specific muta...