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Assessing the association between common functional Nuclear Factor Kappa-b gene…

Vazquez-Coto(D),Perez-Oliveira(S),Menéndez-G… Behav Brain Res 2025-00-05

...NFKBIZ rs3217713 and APOE-Ɛ2/3/4 polymorphisms. Rs7667496 C was increased in the patients (p<0.001) with the CC genotype...

Gene variants in the NF-KB pathway (NFKB1, NFKBIA, NFKBIZ) and risk for early-o…

Coto(E),Reguero(JR),Avanzas(P),Pascual(I),Ma… Immunol Lett 2019-00-00

...NFKBIZ rs3217713, the deletion allele was significantly more frequent in the patients than in controls (0.27 vs. 0.22; p...

IkappaBzeta regulates T(H)17 development by cooperating with ROR nuclear recept…

Okamoto(K),Iwai(Y),Oh-Hora(M),Yamamoto(M),Mo… Nature 2010-04-29

...Nfkbiz gene), as a transcription factor required for T(H)17 development in mice. The ectopic expression of IkappaBzeta i...

Suppression of TCF4 promotes a ZC3H12A-mediated self-sustaining inflammatory fe…

Jiang(Y),Gruszka(D),Zeng(C),Swindell(WR),Gas… JCI Insight 2024-03-12

...NFKBIZ and ZC3H12A expression in an IL-17RA/RE-dependent manner, thus creating a feedback loop. ZC3H12A (MCPIP1/Regnase-...

Genetic susceptibility to invasive pneumococcal disease.

Sangil(A),Arranz(MJ),Güerri-Fernández(R),Pér… Infect Genet Evol 2018-00-00

...NFKBIZ rs645781 (χ2 = 8.25, p = 0.02) and IL1R1 rs3917254 (χ2 = 6.70, p = 0.04) were also associated with IPD risk. When...

The negative feedback loop of NF-κB/miR-376b/NFKBIZ in septic acute kidney inju…

Liu(Z),Tang(C),He(L),Yang(D),Cai(J),Zhu(J),S… JCI Insight 2020-00-17

...NFKBIZ) in both in vitro and in vivo models of septic AKI. Luciferase microRNA target reporter assay further verified NF...

The IL-1R and NFKBIZ pathway mediates immunoregulatory responses and immunother…

Wei(W),Song(Z),Wang(Y),Li(S),Tan(L),Lee(J),C… Leukemia 2026-01-00

...NFKBIZ - IL-17F - MAPK axis that sustains PD-L1 expression via an autocrine loop, while simultaneously inducing proinfla...

A translational silencing function of MCPIP1/Regnase-1 specified by the target …

Behrens(G),Winzen(R),Rehage(N),Dörrie(A),Bar… Nucleic Acids Res 2018-00-04

...NFKBIZ mRNA, which is among the targets of the RNA-binding proteins Roquin-1/2 and MCPIP1/Regnase-1. We present evidence...

miR-4734 conditionally suppresses ER stress-associated proinflammatory response…

Michael(D),Feldmesser(E),Gonen(C),Furth(N),M… FEBS Lett 2023-00-00

...NFKBIZ), which is required for optimal expression of the proinflammatory genes and whose mRNA is targeted directly by mi...

Treatment of psoriasis with NFKBIZ siRNA using topical ionic liquid formulation…

Mandal(A),Kumbhojkar(N),Reilly(C),Dharamdasa… Sci Adv 2020-07-00

...NFKBIZ can be advantageous for treating psoriasis. However, effective delivery of small interfering RNA (siRNA) into the...

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