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Pharmacogenetics and antipsychotic treatment response.

Naumovska(Z),Nestorovska(A K),Filipce(A),S... Pril (Makedon Akad Nauk Ume... 2016-07-15

...RGS4) and points their role as potential biomarkers in everyday clinical practice. Pharmacogenetic testing has predictiv...

RGS4 inhibits angiotensin II signaling and macrophage localization during ren...

Pang(Paul),Jin(Xiaohua),Proctor(Brandon M)... Kidney Int 2016-02-16

...RGS4 expression was suppressed implicating Gα protein activation in an AT2-RGS4-dependent pathway. RGS4 function, specif...

Regulator of G-protein signaling 4: A novel tumor suppressor with prognostic ...

Cheng(Chuanle),Yue(Weiming),Li(Lin),Li(Shu... Biochem Biophys Res Commun 2016-05-27

...RGS4 expression was higher in normal lung tissues than NSCLC specimens (P = 0.003). Further studies demonstrated that RG...

Roles for Regulator of G Protein Signaling Proteins in Synaptic Signaling and...

Gerber(Kyle J),Squires(Katherine E),Hepler... Mol Pharmacol 2016-05-13

...RGS4, RGS7, RGS9-2, and RGS14) that have been clearly demonstrated to serve critical roles in modulating synaptic signal...

Transcriptional Profiling of a Selective CREB Binding Protein Bromodomain Inh...

Chekler(Eugene L Piatnitski),Pellegrino(Je... Chem Biol 2016-07-26

...RGS4) gene in neurons, suggesting a potential therapeutic opportunity for CBP inhibitors in the treatment of neurologica...

Influence of DAOA and RGS4 genes on the risk for psychotic disorders and thei...

Soler(J),Miret(S),Lázaro(L),Parellada(M),M... Eur Psychiatry 2016-09-21

...RGS4) with the risk for psychotic disorders. Our aims were to examine: (i) the relationship between DAOA and RGS4 and th...

M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in ...

Shen(Weixing),Plotkin(Joshua L),Francardo(... Neuron 2016-03-01

...RGS4) activity, and blocked D1 dopamine receptor dependent long-term potentiation (LTP). Furthermore, in a mouse model o...

The Role of Chromosomal Instability and Epigenetics in Colorectal Cancers Lac...

Abdel-Rahman(Wael M),Lotsari-Salomaa(Johan... Gastroenterol Res Pract 2016-04-06

...RGS4, MCTP1, DGKI, OBCAM/OPCML, and GLIPR1) confirmed that they were differentially expressed in clinical specimens. Sin...

Inhibition of the regulator of G protein signalling RGS4 in the spinal cord d...

Bosier(Barbara),Doyen(Pierre J),Brolet(Ama... Br J Pharmacol 2016-10-25

...RGS4 were used to correlate cAMP production and ERK phosphorylation with receptor activation and RGS4 action.,Treatment ...

Decreased levels of RGS4 in the paraventricular nucleus facilitate GABAergic ...

Jung(Soonwoong),Son(Hyeonwi),Lee(Dong Hoon... Biochem Biophys Res Commun 2016-08-08

...RGS4 decrease is attenuated by a GABAB receptor antagonist. These results suggest that RGS4 in the PVN regulates blood c...

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