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The glycosyltransferase ALG3 is an AKT substrate that regulates protein N-glyco…

Navarro-Traxler(AJ),Ghisolfi(L),Lien(EC),Tok… J Biol Chem 2025-09-00

...ALG3 in the amino terminal region at Ser11/Ser13. CRISPR/Cas9-mediated depletion of ALG3 leads to improper glycan format...

Sequential cleavage of the proteins encoded by HNOT/ALG3, the human counterpart…

Hacker(B),Schultheiß(C),Kurzik-Dumke(U) Hum Mol Genet 2018-00-15

...ALG3 encodes two alternatively spliced main transcripts, hNOT-1/ALG3-1 and hNOT-4/ALG3-4, and their 15 truncated derivat...

ɑ1,3-mannosyltransferase promotes the malignant progression of bladder cancer t…

Liu(M),Zhang(J),Zhu(S),Jiang(W),Yan(Y),Zheng… Eur J Med Res 2025-05-02

...ALG3 and POMT2 belong to the mannosyltransferase family, with ALG3 identified as a more reliable diagnostic glycobiomark...

Deficient glycan extension and endoplasmic reticulum stresses in ALG3-CDG.

Daniel(EJP),Edmondson(AC),Argon(Y),Alsharhan… J Inherit Metab Dis 2024-00-00

ALG3-CDG is a rare congenital disorder of glycosylation (CDG) with a clinical phenotype that includes neurological manif...

Inhibition of α-1,3-mannosyltransferase sensitizes head and neck squamous cell …

Hao(Y),Deng(G),Li(B),Cheng(L),Wang(S),Yang(Z) Cell Stress Chaperones 2026-03-00

...ALG3-knockdown cells and a subcutaneous tumor model demonstrated that ALG3 inhibition markedly suppressed HNSCC prolifer...

The glycosyltransferase ALG3 is an AKT substrate that regulates protein N-glyco…

Navarro-Traxler(AJ),Ghisolfi(L),Lien(EC),Tok… bioRxiv 2025-04-03

...ALG3 in the amino terminal region at Ser11/Ser13. CRISPR/Cas9-mediated depletion of ALG3 leads to improper glycan format...

Inhibition of ALG3 stimulates cancer cell immunogenic ferroptosis to potentiate…

Liu(P),Lin(C),Liu(Z),Zhu(C),Lin(Z),Xu(D),Che… Cell Mol Life Sci 2022-06-08

...ALG3, an a-1,3-mannosyltransferase involved in protein glycosylation in the endoplasmic reticulum (ER), can boost the re...

ALG3-CDG: a patient with novel variants and review of the genetic and ophthalmi…

Farolfi(M),Cechova(A),Ondruskova(N),Zidkova(… BMC Ophthalmol 2021-06-05

...ALG3. Our study expands the spectrum of pathogenic variants identified in ALG3. Thirty-three variants in 43 subjects wit...

Arabidopsis thaliana ALG3 mutant synthesizes immature oligosaccharides in the E…

Kajiura(H),Seki(T),Fujiyama(K) Glycobiology 2010-06-00

...ALG3 from other species. In Arabidopsis thaliana, AtALG3 (At2g47760) was identified as alpha1,3-mannosyltransferase. Com...

Nordihydroguaiaretic acid inhibits bladder cancer metastasis through suppressio…

Liu(M),Zhang(J),Zhang(T),Zheng(Q),Li(S) J Transl Med 2025-07-02

...ALG3 expression in bladder cancer patients. Combined measurement of ALG3 in urine and serum samples demonstrated strong ...

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