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HIF1 inhibition targets tumoral and myeloid cells, and is a promising therapy...

Yanushko(D),Pichot(A),Vincent(A),Keime(C),... Cell Death Dis 2026-03-27

...TP53 are commonly mutated tumor suppressors in metastatic PCa, yet the molecular and cellular mechanisms driving aggress...

Impact of allogeneic stem cell transplantation in patients with higher risk m...

Bazinet(A),Bataller(A),Chien(K),Sasaki(K),... Blood Cancer J 2026-03-27

...TP53 status was the most important predictor of post-SCT OS. Patients with TP53-wild type MDS had an OS of 69% at 5 year...

Potential of SERS and proteomics for biomarker detection in cancer cells.

Lilek(D),Mayr(A),Grossinger(C),Rechthaler(... Anal Bioanal Chem 2026-08-00

...TP53 status were utilized to evaluate the effects of etoposide, a DNA-damaging chemotherapeutic agent, and resveratrol, ...

Age-related genomic characterization and therapeutic targets in Chinese breas...

Sui(XY),Song(XQ),Liu(XY),Shao(ZM),Hu(X),Ch... BMC Med 2026-03-27

...TP53 and ERBB2 were more likely to be co-mutated in young women. Patients with TP53 and ERBB2 co-mutation tend to have a...

New 1,2,3-Triazole and Dipyridothiazine Hybrids-Synthesis, Analysis, Cytotoxi...

Martula(E),Bagrowska(W),Strzyga-Łach(P),St... Biomolecules 2026-02-26

...TP53, CDKN1A, BCL-2, and BAX expression for the lead compound TDT2b revealed modulation of chromatin organization, p53-d...

Analysis of RNA Expression Specificity and Commonality in Commonly Used Tool ...

Yang(H),Zhang(C),Chao(X),Chen(J),Ding(Y),Z... Biomolecules 2026-03-17

...TP53) respectively, and numerous other genes are also repeatedly interpreted like them. Thus, it is crucial to reduce su...

Mechanistic Insights into Active Components of Rosa Roxburghii Juice Against ...

Du(Y),Du(Y),Liu(S),Li(J),Tian(L),Yao(L),Li... Antioxidants (Basel) 2026-02-28

...TP53 and the p53 signaling pathway emerging as central regulatory hubs. Quercetin, Epicatechin, Emodin, and Ellagic acid...

Molecular and Microenvironmental Mechanisms of Malignant Transformation in Be...

Giasimakopoulos(P),Mylona(D),Diafas(A),Sta... Diagnostics (Basel) 2026-03-18

...TP53 mutations, and ERBB2 overexpression, along with epigenetic dysregulation through CpG island hypermethylation. Enhan...

Age-Associated Genetic Variations in Breast Cancer: Somatic Mutations and Co-...

Ekinci(B),Orenay-Boyacioglu(S),Erdogdu(IH)... Biomedicines 2026-02-25

...TP53, PIK3CA, PTEN, RAD50, BLM, NF1, AR, BRCA2, and KMT2C. Notably, PIK3CA mutations were significantly more frequent in...

Proposed Role of Circadian Clock Genes in Pathogenesis of HCC: Molecular Subt...

Lu(Z),Zhou(Y),Luo(J),Liu(Z),Xiao(Z) Biomedicines 2026-03-12

...TP53/AXIN1/TERT alterations, strong activation of cell-cycle, E2F, and G2M programs, and an immune-hot yet immunosuppres...

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