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Emerging functions of SRSF1, splicing factor and oncoprotein, in RNA metaboli...

Das(Shipra),Krainer(Adrian R) Mol Cancer Res 2015-06-05

...SRSF1 proto-oncogene in human cancers, and the complex mechanisms and pathways underlying SRSF1-mediated transformation....

SRSF1 shapes 3'-end site selection with differential dependence on U1 snRNP.

Merens(HE),Raicu(AM),Carroll(CL),Kourkoula... bioRxiv 2026-05-05

...SRSF1 levels display shifted 3'-end selection. At PASs modulated by both SRSF1 and U1 snRNP, SRSF1 acts on sites through...

Splice-switching ASOs targeting the AURKA 5' UTR collapse an SRSF1-AURKA-MYC ...

Kral(AJ),Jia(L),Sim(G),Wan(L),Ishigami(Y),... Mol Cell 2026-01-08

...SRSF1-AURKA-MYC oncogenic circuit, wherein SRSF1 regulates AURKA 5' UTR alternative splicing, enhancing AURKA protein ex...

Activities of topoisomerase I in its complex with SRSF1.

Ishikawa(Takao),Krzysko(Krystiana A),Kowal... Biochemistry 2012-05-01

...SRSF1. Our results indicate two features of the unfolded RS domain of SRSF1 containing phosphorylated residues that are ...

Serine Arginine-Rich Splicing Factor 1 (SRSF1) Contributes to the Transcripti...

Moulton(Vaishali R),Gillooly(Andrew R),Per... PLoS One 2016-04-05

...SRSF1) binding to the 3' untranslated region (UTR) of CD3ζ mRNA. We showed that SRSF1 regulates alternative splicing of ...

SRSF1 as a promising biomarker and key player in the pathogenesis of Alzheime...

Liu(Y),Zhao(Y),Yao(Y),Liu(D),Sun(Y),Xu(W),... Mol Med Rep 2026-06-00

...SRSF1 and NDUFB5) were associated with specific immune cell infiltration. SRSF1 was significantly enriched in the p38MAP...

Mutual inhibition between YAP and SRSF1 maintains long non-coding RNA, Malat1...

Wang(Jiayi),Wang(Hongmei),Zhang(Yue),Zhen(... Cell Signal 2014-11-04

...SRSF1) played an opposing role. SRSF1 inhibited YAP activity by preventing its co-occupation with TCF/β-catenin on the M...

RRM1 domain of the splicing oncoprotein SRSF1 is required for MEK1-MAPK-ERK a...

Shimoni-Sebag(Ariel),Lebenthal-Loinger(Ila... Carcinogenesis 2014-01-22

...SRSF1 on some of its endogenous targets. Moreover, we found that SRSF1 elevates the expression of B-Raf and activates th...

Posttranscriptional Regulation of Splicing Factor SRSF1 and Its Role in Cance...

Gonçalves(Vânia),Jordan(Peter) Biomed Res Int 2016-05-13

...SRSF1 localization. In addition, we resume current knowledge on deregulated SRSF1 expression in tumors and describe SRSF...

SRSF1 RNA Recognition Motifs Are Strong Inhibitors of HIV-1 Replication.

Paz(Sean),Lu(Michael L),Takata(Hiroshi),Tr... J Virol 2015-07-27

...SRSF1. Here we report that SRSF1 can downregulate the replication of B, C, and D subtype viruses by >200-fold in a cell ...

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