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14-3-3 proteins interact with a hybrid prenyl-phosphorylation motif to inhibi...

Riou(Philippe),Kjær(Svend),Garg(Ritu),Purk... Cell 2013-06-25

...Rnd2, and geranylgeranylated Rap1A interact similarly with 14-3-3. In contrast to the canonical GTP/GDP switch that regu...

Interaction characteristics of Plexin-B1 with Rho family proteins.

Fansa(Eyad Kalawy),Dvorsky(Radovan),Zhang(... Biochem Biophys Res Commun 2013-08-27

...Rnd2, Rnd3, and RhoD, but not to RhoA, Cdc42, RhoG, or Rif. Interestingly, Rnd1 competitively displaces the Rac1 from B1...

Rnd1 and Rnd3 targeting to lipid raft is required for p190 RhoGAP activation.

Oinuma(Izumi),Kawada(Kana),Tsukagoshi(Kiyo... Mol Biol Cell 2012-09-28

The Rnd proteins Rnd1, Rnd2, and Rnd3/RhoE are well known as key regulators of the actin cytoskeleton in various cell ty...

Lysophosphatidic acid induces neurite branch formation through LPA3.

Furuta(Daisuke),Yamane(Masayuki),Tsujiuchi... Mol Cell Neurosci 2012-11-09

...Rnd2/Rho7 or an Rnd2 effector rapostlin abolished LPA(3)-mediated neurite branching. The LPA(3) agonist 2(S)-OMPT or LPA...

The GTPase-deficient Rnd proteins are stabilized by their effectors.

Goh(Liuh Ling),Manser(Ed) J Biol Chem 2012-11-19

...Rnd2, and Rnd3 stability is acutely dependent on interaction with their effectors such as Syx or p190 RhoGAP. Although R...

Proneural transcription factors regulate different steps of cortical neuron m...

Pacary(Emilie),Heng(Julian),Azzarelli(Robe... Neuron 2011-06-29

...Rnd2. Here, we show that another proneural factor, Ascl1, promotes neuronal migration in the cortex through direct regul...

Rnd-ing up RhoA activity to link neurogenesis with steps in neuronal migratio...

Li(Jingjun),Anton(E S) Dev Cell 2011-06-16

...Rnd2 and Rnd3 in newborn cortical neurons, leading to compartmentalized modulation of RhoA signaling and differential co...

COUP-TFI promotes radial migration and proper morphology of callosal projecti...

Alfano(Christian),Viola(Luigi),Heng(Julian... Development 2011-12-27

...Rnd2 expression at the post-mitotic level along the rostrocaudal axis of the neocortex. Restoring correct Rnd2 levels in...

A de novo complete BRCA1 gene deletion identified in a Spanish woman with ear...

Garcia-Casado(Zaida),Romero(Ignacio),Ferna... BMC Med Genet 2011-12-14

...RND2, ΨBRCA1, BRCA1 and NBR2 complete genes.,This finding supports the large genomic rearrangement screening of BRCA gen...

Structural basis of Rnd1 binding to plexin Rho GTPase binding domains (RBDs).

Wang(Hui),Hota(Prasanta K),Tong(Yufeng),Li... J Biol Chem 2011-09-16

...Rnd2 but associate with Rnd1 only weakly. The structural basis of this differential Rnd1 GTPase binding to plexin RBDs r...

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