Katoh(Masaru) Expert Rev Proteomics 2016-01-22

...ASXL2 and ASXL3 are epigenetic scaffolds for BAP1, EZH2, NCOA1, nuclear receptors and WTIP. Here, functional proteomics ...

Izawa(Takashi),Rohatgi(Nidhi),Fukunaga(Tom... Cell Rep 2016-03-24

ASXL2 is an ETP family protein that interacts with PPARγ. We find that ASXL2-/- mice are insulin resistant, lipodystroph...

Agostini(Marco),Zangrando(Andrea),Pastrell... Cancer Biol Ther 2016-05-12

...ASXL2. Real time PCR confirmed that XRCC3 is overexpressed in responders group and HFM1 and ASXL2 showed a positive tren...

Daou(Salima),Hammond-Martel(Ian),Mashtalir... J Biol Chem 2016-03-18

...ASXL2, but not ASXL1, protein stability. Notably, cancer-associated loss of BAP1 expression results in ASXL2 destabiliza...

Sahtoe(Danny D),van Dijk(Willem J),Ekkebus... Nat Commun 2016-06-09

...ASXL2 or ASXL3 to increase BAP1's affinity for ubiquitin on H2A, to drive the deubiquitination reaction. The reaction is...

Ahn(Jae-Sook),Kim(Hyeoung-Joon),Kim(Yeo-Ky... Biol Blood Marrow Transplan... 2016-09-29

...ASXL2, FAT1, DNAH11, and GATA2 mutations in diagnostic samples and analyzed for long-term outcomes after allogeneic HCT....

Huether(Robert),Dong(Li),Chen(Xiang),Wu(Ga... Nat Commun 2015-09-30

...ASXL2, CREBBP, EZH2, MLL2, USP7, ASXL1, NSD2, SETD2, SMC1A and ZMYM3. We identify novel loss-of-function mutations in th...

McGinley(Andrea L),Li(Yanyang),Deliu(Zane)... Genesis 2015-02-20

...ASXL2 and ASXL1, two homologous chromatin factors, as novel regulators of heart development. Asxl2(-/-) fetuses have red...

Micol(Jean-Baptiste),Duployez(Nicolas),Boi... Blood 2015-04-24

...ASXL2 mutant t(8;21) AML patients and their wild-type counterparts, patients with ASXL1 or ASXL2 mutations had a cumulat...

Balbás-Martínez(Cristina),Sagrera(Ana),Car... Nat Genet 2014-02-12

...ASXL2 and BPTF), cell division (STAG2, SMC1A and SMC1B) and DNA repair (ATM, ERCC2 and FANCA). STAG2, a subunit of cohes...