...TP53 are common abnormalities in colorectal cancer, the determination of K-ras mutation combined with TP53 gene mutation...
...TP53 mutation showed a complete response. In patients with TP53 mutation, compared with patients without TP53 mutation, ...
...TP53 mutant tumors harbor 56% germline TP53 mutations, which are not observed in children with WNT/TP53 mutant tumors. F...
...TP53 is a key regulator of genomic stability, frequently altered across human cancers. In hematologic malignancies, TP53...
...TP53, others may be recessive. Point mutations of TP53 tend to occur on evolutionary conserved positions. However, the T...
...TP53 (tumor protein 53), MDM2 (TP53 E3 ubiquitin protein ligase homolog), PERP (TP53 apoptosis effector), and USP7 (ubiq...
...TP53 mutations, 13 (11%) copy loss without mutation, and 48 (41%) lacked both [defined as TP53-wild-type (wt)]. Patients...
...TP53 genetic alterations, the clinical significance of TP53 mutations in OSCC remains poorly understood. Thus, we set ou...
...TP53 are more frequent than previously reported. These findings emphasize the importance of thorough screening of TP53 m...
...TP53 alterations. Understanding the biology and clinical impact of TP53 mutations is vital for risk stratification and t...
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