...TP53, caspases, and XIAP, activating apoptosis, necroptosis, and fibrosis. Compensatory antioxidant responses are activa...
...tp53 mediates mtp53-PARP and mtp53-Poly (ADP-ribose) (PAR) interactions that facilitate S phase progression [4, 5]. The ...
...TP53 loss) produce coherent UPS protein-quantitative trait locus (pQTL) signatures. Two case studies (UBR5 and TRIM28) i...
...TP53 family member located on chromosome 1p36, encodes both transcriptionally active (TAp73) and dominant-negative (ΔNp7...
...TP53. Due to the high TMB, off-label Pembrolizumab was initiated. Radiological evaluations at 3 and 6 months showed a ma...
...TP53-mutated AML based on clinical outcomes comparable to other available standards of care. However, TP53-mutated AML i...
...TP53 mutations significantly correlated with shorter PFS, while ASXL1 mutations correlated with longer PFS. This chemoth...
...TP53) and by later events linked to malignant transformation (e.g., CDKN2A/B homozygous deletion). Despite integrated gr...
...TP53, as well as the adherent cell line HS-5. RESULTS: Repeated analyses confirmed high sensitivity and reproducibility ...
...TP53, PALB2, CHEK2, and EGFR. Prevalence rates varied by gene, cohort characteristics, ethnicity, and histology with spe...
山东省济南市章丘区文博路2号
齐鲁师范学院 genelibs生信实验室
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