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microRNA-137 promotes apoptosis in ovarian cancer cells via the regulation of...

Li(Xiaodi),Chen(Wei),Zeng(Wenshu),Wan(Chun... Br J Cancer 0000-00-00

...CRISPR/Cas9 inhibited apoptosis and upregulated XIAP in A2780 cells. Furthermore, the effect of miR-137 on apoptosis cou...

The adaptor protein Disabled-2: new insights into platelet biology and integr...

Tsai(Hui-Ju),Tseng(Ching-Ping) Thromb J 0000-00-00

...CRISPR and TALEN in the generation of genetically modified animals, the progress in gaining new insights into the functi...

RNF43 germline and somatic mutation in serrated neoplasia pathway and its ass...

Yan(Helen H N),Lai(Jeffrey C W),Ho(Siu Lun... Gut 0000-00-00

...CRISPR-induced RNF43 mutations had reduced dependency on R-spondin1.,These results illustrate the importance of RNF43, a...

Impaired motor activity in a CRISPR SCA5 L253P knock-in mouse is associated w...

Avery(AW),O'Callaghan(BL),Thiel(MT),Denha(... bioRxiv 2026-03-17

...CRISPR knock-in mouse to determine the in vivo impact of L253P on Purkinje neurons and motor activity, and to establish ...

Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and...

Yuan(S),Wei(N),Ma(W),Hu(M),Zhang(B),Gao(L)... Andrology 2026-03-27

...CRISPR/Cas9 system, the natural adult (9 weeks) mice, aging (9 months) mice, and wild-type MLTC-1 cells were used as con...

Therapeutic potential of cAMP-mediated lysosomal pH modulation in ATP6V1B2-re...

Zheng(L),Zhao(W),Yang(G),Qiu(S),Li(Y),Gao(... Cell Death Discov 2026-03-27

...CRISPR/Cas9 for dynamic lysosomal pH monitoring via ratiometric RpH-LAMP1-3×flag imaging to evaluate pathophysiological ...

Enhancing Synthesis Efficiency in Microbial 1,5-Pentanediol Production Throug...

Deng(H),Meng(F),Sun(Y),Song(Y),Zhao(C),Wan... Microorganisms 2026-03-22

...CRISPR interference (CRISPRi)-mediated repression. Reverse engineering confirmed that overexpression of fecA (encoding a...

12-hydroxylauric acid, a novel growth regulator, promotes plant organ develop...

Peng(Y),Zhang(M),Tan(Z),Lou(H),Yang(B),Zha... J Integr Plant Biol 2026-07-00

...CRISPR knockout mutants exhibited reductions in silique length, seed size, and seed number per silique. Enzyme assays re...

A LINE-1 retrotransposon promotes SEMA3C expression as a cis-regulatory enhan...

Xia(Q),Feng(J),Pan(J),Deng(W),Weng(X),Jian... Sci China Life Sci 2026-06-00

...CRISPR activation (CRISPRa) assay, we show that the LINE-1 retrotransposon L1Md_T within Sema3c (Sema3c_L1Md_T) is derep...

Telomere recapping prevents pathogenic telomere-to-mitochondrial DNA communic...

Zhao(Y),Bao(X),Xiong(W),Wan(X),Yu(Q),Wang(... Cardiovasc Res 2026-05-22

...CRISPR/Cas9 genome editing, we demonstrated that JV101 is recruited by TPP1 through TEL patch to telomeric ends. JV101 r...

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