...TP53 (red) yeast colonies resulting from monoclonal expansion of cells with mutated TP53. The presence of TP53 mutations...
...TP53 mutation, but de novo (primary) GBM is usually independent of TP53 alteration. However, the subpopulation of TP53 a...
...TP53 related radioresistance and can be used to sensitize TP53 mutant tumors for radiation. We examined the subgroup-spe...
...TP53 mutations, and for mutations in genes frequently mutated in ECs. TP53 mutations were found in 15% of EECs and 88% o...
...TP53 is critical for its tumor suppressive activity, the mechanisms by which TP53 engages the genome in the context of c...
...TP53) mutation and with limited targeted therapies. Despite being clinically advantageous, direct targeting of mutant TP...
...TP53 GOF mutations than in those wild type for TP53 (median of 12.0 versus 31.4 months, P = 0.0016) or those with TP53 n...
...TP53 regulates the expression of many genes, but the regulation of expression of TP53 itself is poorly understood. Recen...
...TP53 mutations and over-expression of the protein, 2 cell lines showed TP53 mutations but no p53 expression, and 2 cell ...
...TP53 gene, and were confirmed by sequencing. Abnormal TP53 protein staining was found in 55% of the primary samples, usi...
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