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Molecular Profile of Advanced Radioiodine-refractory Thyroid Cancer and Respo...

Minaldi(E),Ramone(T),Ciampi(R),Romei(C),Ca... J Clin Endocrinol Metab 2026-08-13

...TP53 were mutated in 57.1% and 6.1%. No driver mutations were found in 34.6%. Driver mutations co-occurred with TERT or ...

Molecular Profiling and Treatment Outcomes in Uterine Serous Carcinoma: Progn...

Svarna(A),Liontos(M),Goula(K),Pardali(K),K... Curr Oncol 2026-02-24

...TP53, ER, PR, HER2, and MMR status), and survival outcomes were collected. Patients were first staged by FIGO 2009 and r...

Interplay Between p53 and Wnt/β-Catenin Signaling in Colorectal Cancer: Assoc...

Chiba(S),Oikawa(S),Mitomi(H),Sasaki(Y),Hob... Curr Oncol 2026-03-21

...TP53 alterations and Wnt/β-catenin signaling in colorectal cancer (CRC) remains unclear regarding mismatch repair (MMR) ...

Nucleic Acids on the Surface and Lumen of Tumor-Derived Small Extracellular V...

Gluszko(A),Kania(D),Hong(CS),Pietrowska(M)... Cells 2026-03-13

...TP53 gene fragment for a mutational signature was performed. Results: Enzymatic and microscopic studies of TEX showed th...

Cell-Free DNA as Biomarker in Oral Squamous Cell Carcinoma: Dynamics, Mutatio...

Veiga(P),Barroso(L),Pires(LM),Mano(C),Cara... Cells 2026-03-23

...TP53, PIK3CA, KRAS, APC, and FBXW7. Urine cfDNA also captured several mutations absent from plasma or tissue, supporting...

Biomarkers in Colorectal Cancer: Clinically Relevant Diagnostic and Prognosti...

Whitmer(R),Sepulveda(J),Gandhi(J),Puri(I),... J Pers Med 2026-02-28

...TP53, KRAS, NRAS, SMAD4, PIK3CA and BRAF, provide valuable insights into tumor biology, therapeutic resistance, and resp...

Case report: Dynamic genetic profiles reveal a patient with myelodysplastic n...

Guo(G),Cheng(H),Sun(M),Liu(L),Qin(J),Liu(Y... Discov Oncol 2026-03-27

...TP53 via a targeted 521-gene hematologic disorder panel. Treatment commenced with azacitidine and supportive care, leadi...

Mapping the genetic landscape of hereditary diffuse-type gastric cancer progr...

Kemp(LJS),van Cruchten(R),Lomans(R),Rutger... Gastric Cancer 2026-05-00

...TP53, and genes involved in TGF-β signaling, cell adhesion, and actomyosin contractility (e.g., SMAD4, FAT4, RHOA). Copy...

Clinical strategies for leukemia management: Recommendations from the Bridgin...

Carraway(HE),DeAngelo(DJ),Wang(ES),Komrokj... Leuk Res 2026-05-00

...TP53-mutated MDS. For ALL, recommendations highlighted avoiding transplant in most Philadelphia chromosome-positive pati...

Fragile histidine triad (FHIT) suppresses gastric cancer via translational re...

Hu(H),Wang(Y),Qi(H),Liu(G),Wang(R),Shen(J) J Biol Chem 2026-05-00

...TP53, by demethylating H3K27me3 at their promoters. In addition, KDM6B negatively regulates cytokine-related genes, such...

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