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The tumour suppressor RBM5 activates the helicase DHX15 to regulate splicing.

Liu(S),Su(T),Huang(J),Lin(CH),Black(DL),Da... Res Sq 2026-04-08

...DHX15 and places this DExH-box helicase on the pre-mRNA as it exits SF3B1, poised for branch helix unwinding. DHX15 bind...

PML::RARA-negative APL-mimicking AML with a novel KMT2C::CREB3L2 fusion and R...

Ma(L),Wu(M) Ann Hematol 2026-04-18

...DHX15. Although complete remission was achieved after induction therapy, the response to IA and subsequent CHA chemother...

The tumour suppressor RBM5 activates the helicase DHX15 to regulate splicing.

Liu(S),Su(T),Huang(J),Lin(CH),Black(DL),Da... bioRxiv 2026-03-27

...DHX15 and places this DExH-box helicase on the pre-mRNA as it exits SF3B1, poised for branch helix unwinding. DHX15 bind...

Plakophilin 1 suppresses keratinocyte innate immune responses through DExD/H ...

Keil(R),Misiak(D),Hüttelmaier(S),Tellkamp(... Cell Mol Immunol 2026-08-19

...DHX15. This limits their ability to activate the MDA5-MAVS signaling axis and prevents excessive activation of IRF3- and...

Oncogenic DHX15 mutation enhances mitochondrial metabolism and sustains leuke...

Li(Q),Xing(P),Xu(J),Li(J),Chen(L),Li(X),Ba... Leukemia 2026-08-21

...DHX15 mutations exhibit an inferior prognosis. Functional analysis demonstrates that DHX15R222G cooperates with AML1-ETO...

DHX15 as a novel immune-related prognostic biomarker in breast cancer: An int...

Li(F),Yue(Q),Li(J) Oncol Lett 2026-10-00

...DHX15 in BC, in addition to its underlying molecular mechanisms, remain unclear. DHX15, a key RNA helicase involved in s...

DHX15 affects AML1-ETO9a splicing together with HNRNPL, RBM33 in AML1-ETO-pos...

Liu(Q),Wang(X),Fan(J),Zheng(Y),Ye(L),Chang... Br J Haematol 2026-07-12

...DHX15 (DEAH-box helicase 15) in AE9a splicing and AML progression. Clinically, higher expressed DHX15 is associated with...

DEAH-Box RNA Helicases in the Spliceosome: Advances in Structure and Function...

Chen(Z) FASEB J 2026-02-28

...DHX15/Prp43, and DHX35-bound to their RNA targets within distinct spliceosomal states. These structures reveal precise r...

Grass carp reovirus VP35 hijacks DHX15 into phase-separated inclusion bodies ...

Zhang(C),Lv(Z),Zeng(W),Zhang(YA),Tu(J) Cell Commun Signal 2026-02-09

...DHX15 from nucleus to the cytoplasm VIBs and degrades DHX15 via lysosomal pathway. Our findings provide a novel immune e...

Structural basis of the regulation by CDK11 kinase of early spliceosome activ...

Zhang(Z),Kumar(V),Panta(S),Zhong(J),Dybkov... Nat Commun 2026-07-03

...DHX15 at the N-terminal region of SF3B1HEAT, assisted by the SR140/SPF45/CHERP/SUGP1 protein complex. These results sugg...

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