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Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic stud...

样本量:6 物种:Homo sapiens 类型:ChIP-seq 2016年10月25日

...CRISPR-Cas9 mediated genome editing in the MCF-7 breast cancer cell line, generating MCF-7-Y537S. MCF-7-Y537S cells enco...

Transcriptome of iPSC-derived Neural Cells with Heterozygous Knockout in CHD8

样本量:8 物种:Homo sapiens 类型:RNA-seq of coding RNA 2015年11月5日

...CRISPR/Cas9 technology to knockout one copy of CHD8 in induced pluripotent stem cells (iPSCs) to mimic the loss of funct...

RNA-seq of coding RNA from DDX6 knockout human haploid (HAP1) cells

样本量:4 物种:Homo sapiens 类型:RNA-seq of coding RNA 2017年7月25日

...CRISPR-Cas9 and performed RNA-seq on coding RNA from DDX6 KO and WT cells. This data was used to determine if ISGs were ...

RNA-seq of coding RNA from USP14 knockout human haploid (HAP1) cells

样本量:4 物种:Homo sapiens 类型:RNA-seq of coding RNA 2017年7月25日

...CRISPR-Cas9 and performed RNA-seq on coding RNA from USP14 KO and WT cells. This data was used to determine if ISGs were...

Rapid functional annotation of native enhancers in embryonic stem cells with ...

样本量:1 物种:Mus musculus 类型:ChIP-seq 2015年3月3日

Gene regulatory elements such as enhancers have profound effects on cellular function, health and disease. Our understan...

RNAseq of Salmo salar parrs with CRISPR/Cas9 induced knockout in the elovl2 g...

样本量:58 物种:Salmo salar 类型:RNA-seq of coding RNA 2019年4月30日

...CRISPR-mediated elovl2 knockout, we have shown that elovl2 is crucial for multi-tissue synthesis of 22:6n-3 in vivo and ...

A CRISPR-based screen identifies genes essential for West Nile virus-induced ...

样本量:6 物种:Homo sapiens 类型:other 2015年7月5日

...CRISPR/Cas9. HEK 293FT cells were infected with lentivirus expressing sgRNAs and then transfected with a Cas9 expressing...

A combined genomic approach unveils the transcriptional basis of heterogeneit...

样本量:29 物种:Homo sapiens 类型:RNA-seq of coding RNA 2016年1月18日

...CRISPR-Cas9 clones, 3 ELF3-deleted CRISPR-Cas9 clones and 2 wt clones) and CFPAC1 cells ectopically expressing ZEB1 or e...

Microarray analysis of HCT116 cells with and without a 1.4kb deletion

样本量:6 物种:Homo sapiens 类型:transcription profiling by array 2016年8月16日

...CRISPR/Cas9 mediated 1.4kb deletion of the genomic region harboring rs7903146 in the HCT116 cell line followed by global...

CRISPR-Cas9 combinatorial KO of epigenetic regulators in human ovarian cancer...

样本量:12 物种:Homo sapiens 类型:RNA-seq of coding RNA 2015年12月17日

We sequenced polyA mRNA from OVCAR8-ADR-Cas9 cells in which one or two of 3 epigenetic regulators (BRD4, KDM4C, KDM6B) h...

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