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Inhibitor of apoptosis proteins as promising therapeutic targets in chronic l...

样本量:12 物种:Homo sapiens 类型:transcription profiling by array 2015年3月31日

...TP53 mutation responded significantly better to BV6 than samples with unknown or favourable prognosis e.g. 13q deletion....

Whole Genome Sequencing Informs Therapeutic Selection for Pancreatic Cancer

样本量:100 物种:Homo sapiens 类型:comparative genomic hybridization by ... 2015年2月27日

...TP53, SMAD4, CDKN2A, ARID1A, ROBO2) and novel candidate drivers of pancreatic carcinogenesis (KDM6A and PREX2). Patterns...

Clonal evolution in relapsed NPM1 mutated acute myeloid leukemia

样本量:159 物种:Homo sapiens 类型:genotyping by array 2013年5月30日

...TP53 (n=2), NF1 (n=2), WT1 (n=3), FHIT (n=2)] and homozygous FLT3 mutations acquired via UPD13q (n=7). DNMT3A mutations ...

Gene expression profiling by DNA microarray in Colo741 cell line transfected ...

样本量:6 物种:Homo sapiens 类型:transcription profiling by array 2008年12月17日

...TP53, are considered to have an important role both in the carcinogenesis and in the colorectal tumor progression. The ...

The MYC-MIZ1 interaction defines tumor identity

样本量:23 物种:Mus musculus 类型:ChIP-seq, RNA-seq of coding RNA 2016年1月21日

...TP53 mutations and G3 MBs characterized by C-MYC (MYC) overexpression in ~17% of cases from gene amplification with stem...

Genomic and Transcriptomic Hallmarks of Poorly-Differentiated and Anaplastic ...

样本量:37 物种:Homo sapiens 类型:transcription profiling by array 2016年2月15日

...TP53, TERT promoter, PI3K/AKT/mTOR pathway effectors, SWI/SNF subunits and histone methyltransferases. BRAF and RAS are ...

Comprehensive Analysis of Recurrence-Associated Small Non-Coding RNAs in Esop...

样本量:18 物种:Homo sapiens 类型:transcription profiling by array 2016年6月30日

...TP53, DNA damage response and cell cycle genes. nc886 inhibits minor splicing to suppress expression of certain oncogene...

Array CGH-based Characterization of Genetic Alterations in Pulmonary Neuroend...

样本量:148 物种:Homo sapiens 类型:comparative genomic hybridization by ... 2010年4月22日

...TP53 gene and the MYC family members were observed more frequently in SCLC. These findings suggest the existence of part...

Synergistic Tumor Suppressor Activity of E-cadherin and p53 in a Conditional ...

样本量:6 物种:Mus musculus 类型:transcription profiling by array 2011年12月4日

...TP53 are also frequently found in DGCs. To examine the synergistic effect of loss of E-cadherin and p53 on gastric carci...

A Molecular Taxonomy of Urothelial Carcinoma

样本量:308 物种:Homo sapiens 类型:transcription profiling by array 2012年5月23日

...TP53 mutations. The expression of key proteins was validated by IHC on TMA. A further inspection indicated that the subt...

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