样本量：165 物种：Homo sapiens, Mus musculus 类型：genotyping by high throughput sequencing 2018年9月25日

CRISPR/Cas9-mediated base editing allows to interchange purine bases or pyrimidine bases independent of homology directe...

样本量：6 物种：Homo sapiens 类型：RNA-seq of coding RNA 2017年3月5日

...CRISPR/Cas9 method. Here we studied differential gene expression from wild type and RNH1 knock out K562 cells by RNA-Seq...

样本量：4 物种：Homo sapiens, Homo sapiens 类型：RNA-seq of coding RNA from single cel... 2021年11月3日

...CRISPR/Cas9 scarring, and single-cell transcriptomics to analyze state and lineage relationships in iPSC-derived systems...

样本量：14 物种：Homo sapiens, Homo sapiens 类型：Cell line - Single-cell sequencing, R... 2021年11月3日

...CRISPR/Cas9 scarring, and single-cell transcriptomics to analyze state and lineage relationships in iPSC-derived systems...

样本量：9 物种：Homo sapiens 类型：RNA-seq of coding RNA 2015年8月10日

...CRISPR/Cas9 to introduce the P95H mutation to SRSF2 in K562 leukemia cells, generating an isogenic model so that splicin...

样本量：7 物种：Mus musculus 类型：ChIP-seq, RNA-seq of coding RNA 2014年12月9日

...CRISPR strategy. Allele-specific of Sox2 transcripts in heterozygous enhancer-deletion clones showed that the enhancer a...

样本量：23 物种：Homo sapiens 类型：transcription profiling by array 2015年1月18日

...CRISPR/Cas9 or lentivirus vector system. Each engineered gene and engineered methods are described as a single alphabet ...

样本量：84 物种：Saccharomyces cerevisiae 类型：other 2016年1月18日

...CRISPR interference (CRISPRi) has been used in human cells lines, however the rules for designing effective guide RNAs (...

样本量：12 物种：Homo sapiens 类型：RNA-seq of coding RNA 2019年2月25日

...CRISPR/Cas9 to integrate an A>G mutation in the SF3B1 consensus coding sequence to change the 700th codon from lysine to...

样本量：384 物种：Homo sapiens 类型：RNA-seq of coding RNA from single cel... 2019年11月1日

...CRISPR-Cas9 corrected isogenic control iPSC (SOD1 E100E) were used as control. Survival analysis indicated that at 44 da...