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4C and Capture-C in HCT116, NCM460 cells and colon tissue

样本量:7 物种:Homo sapiens 类型:DNA-seq 2016年8月15日

...CRISPR/Cas9 mediated 1.4kb deletion of the genomic region harboring rs7903146 in the HCT116 cell line followed by global...

CRISPR-Cas9 screening of lncRNAs and protein coding genes involved in the tra...

样本量:15 物种:Homo sapiens, synthetic construct, Ho... 类型:DNA-seq, Cell line - High-throughput ... 2022年4月25日

...CRISPR Knockout) library to knockout lncRNAs and protein coding genes (pc-genes) overexpressed along the seven days the ...

Expression data from Ribonuclease Inhibitor (RI/Rnh1) deficient Human K562 cells

样本量:6 物种:Homo sapiens 类型:RNA-seq of coding RNA 2017年3月5日

...CRISPR/Cas9 method. Here we studied differential gene expression from wild type and RNH1 knock out K562 cells by RNA-Seq...

NGS data from ‘Treatment of a metabolic liver disease by in vivo genome base ...

样本量:165 物种:Homo sapiens, Mus musculus 类型:genotyping by high throughput sequencing 2018年9月25日

CRISPR/Cas9-mediated base editing allows to interchange purine bases or pyrimidine bases independent of homology directe...

Lineage recording in human cerebral organoids (microdissected)

样本量:4 物种:Homo sapiens, Homo sapiens 类型:RNA-seq of coding RNA from single cel... 2021年11月3日

...CRISPR/Cas9 scarring, and single-cell transcriptomics to analyze state and lineage relationships in iPSC-derived systems...

Lineage recording in human cerebral organoids (whole organoids)

样本量:14 物种:Homo sapiens, Homo sapiens 类型:Cell line - Single-cell sequencing, R... 2021年11月3日

...CRISPR/Cas9 scarring, and single-cell transcriptomics to analyze state and lineage relationships in iPSC-derived systems...

Disease-associated mutation in SRSF2 misregulates splicing by altering RNA bi...

样本量:9 物种:Homo sapiens 类型:RNA-seq of coding RNA 2015年8月10日

...CRISPR/Cas9 to introduce the P95H mutation to SRSF2 in K562 leukemia cells, generating an isogenic model so that splicin...

CRISPR reveals a distal murine-specific enhancer required for Sox2 expression...

样本量:7 物种:Mus musculus 类型:ChIP-seq, RNA-seq of coding RNA 2014年12月9日

...CRISPR strategy. Allele-specific of Sox2 transcripts in heterozygous enhancer-deletion clones showed that the enhancer a...

mRNA expression data from adenoma, gene modified, and colorectal cancer organoid

样本量:23 物种:Homo sapiens 类型:transcription profiling by array 2015年1月18日

...CRISPR/Cas9 or lentivirus vector system. Each engineered gene and engineered methods are described as a single alphabet ...

Parallel quantitative CRISPR interference in yeast identifies chemical-geneti...

样本量:84 物种:Saccharomyces cerevisiae 类型:other 2016年1月18日

...CRISPR interference (CRISPRi) has been used in human cells lines, however the rules for designing effective guide RNAs (...

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