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Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic stud...

样本量:6 物种:Homo sapiens 类型:ChIP-seq 2016年10月25日

...CRISPR-Cas9 mediated genome editing in the MCF-7 breast cancer cell line, generating MCF-7-Y537S. MCF-7-Y537S cells enco...

Transcriptome of iPSC-derived Neural Cells with Heterozygous Knockout in CHD8

样本量:8 物种:Homo sapiens 类型:RNA-seq of coding RNA 2015年11月5日

...CRISPR/Cas9 technology to knockout one copy of CHD8 in induced pluripotent stem cells (iPSCs) to mimic the loss of funct...

Cross-species screening platforms identify EPS-8 as a critical link for mitoc...

样本量:18 物种:Caenorhabditis elegans, Homo sapiens,... 类型:RNA-seq of coding RNA, Cell line - Hi... 2021年12月1日

...CRISPR-Cas9 screening of 3.5ng/mL rotenone-treated NPCs versus an ethanol control (treatments include 8 days and 23 days...

scRNAseq of AKP Mex3a KO mouse colorectal organoids in FOLFIRI treatment

样本量:11 物种:Mus musculus, Mus musculus 类型:RNA-seq of coding RNA from single cel... 2022年5月16日

...CRISPR were sequenced in three different conditions. Live organoids (DAPI negative) were sorted in Control, after 2 days...

RNA-seq of coding RNA from DDX6 knockout human haploid (HAP1) cells

样本量:4 物种:Homo sapiens 类型:RNA-seq of coding RNA 2017年7月25日

...CRISPR-Cas9 and performed RNA-seq on coding RNA from DDX6 KO and WT cells. This data was used to determine if ISGs were ...

RNA-seq of coding RNA from USP14 knockout human haploid (HAP1) cells

样本量:4 物种:Homo sapiens 类型:RNA-seq of coding RNA 2017年7月25日

...CRISPR-Cas9 and performed RNA-seq on coding RNA from USP14 KO and WT cells. This data was used to determine if ISGs were...

Rapid functional annotation of native enhancers in embryonic stem cells with ...

样本量:1 物种:Mus musculus 类型:ChIP-seq 2015年3月3日

Gene regulatory elements such as enhancers have profound effects on cellular function, health and disease. Our understan...

Identification of ETO2 direct target genes through integration of transcripto...

样本量:44 物种:Homo sapiens, Homo sapiens 类型:RNA-seq of coding RNA 2023年7月2日

...CRISPR/Cas9 system. Gene expression profiling (RNAseq) and chromatin immunoprecipitation followed by high-throughput seq...

Remodelling of the DNA methylation landscape of leukemic cells upon FOSL2 KO ...

样本量:4 物种:Homo sapiens, Homo sapiens 类型:Cell line - Methylation microarray, m... 2021年3月12日

In this dataset we used the most recent Illumina MethylationEPIC Beadchip platform to describe the genome-wide DNA methy...

RNAseq of Salmo salar parrs with CRISPR/Cas9 induced knockout in the elovl2 g...

样本量:58 物种:Salmo salar 类型:RNA-seq of coding RNA 2019年4月30日

...CRISPR-mediated elovl2 knockout, we have shown that elovl2 is crucial for multi-tissue synthesis of 22:6n-3 in vivo and ...

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