Tubulin structure: insights into microtubule properties and functions.

Current opinion in structural biology ·Vol. 8 ·No. 6 ·1998-12-00 ·Pages 785-91

Downing KH, Nogales E

Abstract

The structure of tubulin has recently been determined by electron crystallography, paving the way for a clearer understanding of the unique properties of tubulin that allow its varied functions within the cell. Some of the ongoing work on tubulin can be interpreted in terms of its structure, which can serve to guide future studies.

MeSH Terms

Colchicine/metabolism Microtubules/metabolism Models, Molecular Paclitaxel/metabolism Protein Conformation Protein Folding Tubulin/chemistry,metabolism

Chemicals

Tubulin Paclitaxel Colchicine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Downing K H

Donner Laboratory Life Science Division Lawrence Berkeley National Laboratory Molecular and Cell Biology University of California Berkely CA 94720 USA. khdowning@lbl.gov

Nogales E

Article Info

Journal

Current opinion in structural biology

Abbr.

Curr Opin Struct Biol

ISSN

0959-440X

DOI

10.1016/s0959-440x(98)80099-7

khdowning@lbl.gov

Published

1998-12-00

Pages

785-91

Language

English

Region

England

NLM ID

9107784

Subset

External Links

PubMed source DOI: 10.1016/s0959-440x(98)80099-7 View journal details

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